How to classify antipsychotics: time to ditch dichotomies?

McCutcheon, Robert A; Cannon, Alistair; Parmer, Sita; Howes, Oliver D

McCutcheon, Robert A; Cannon, Alistair; Parmer, Sita; Howes, Oliver D.

Afiliação

McCutcheon RA; Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK; Oxford Health NHS Foundation Trust, Oxford, UK; and Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Cannon A; South London and Maudsley NHS Foundation Trust, London, UK.
Parmer S; South London and Maudsley NHS Foundation Trust, London, UK.
Howes OD; Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK; South London and Maudsley NHS Foundation Trust, London, UK; Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK; and H. Lundbeck A/S, Copen

Br J Psychiatry ; 224(1): 20-25, 2024 01.

Article em En | MEDLINE | ID: mdl-37960929

RESUMO

The dichotomies of 'typical/atypical' or 'first/second generation' have been employed for several decades to classify antipsychotics, but justification for their use is not clear. In the current analysis we argue that this classification is flawed from both clinical and pharmacological perspectives. We then consider what approach should ideally be employed in both clinical and research settings.

Assuntos

Antipsicóticos; Esquizofrenia; Humanos; Antipsicóticos/uso terapêutico; Esquizofrenia/tratamento farmacológico

Palavras-chave

Schizophrenia; medication; nomenclature; pharmacology; psychosis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esquizofrenia / Antipsicóticos Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article

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