Et tu neutrophils? The brain reprograms neutrophils to facilitate tumor progression.

Ross, James L; Hambardzumyan, Dolores

Ross, James L; Hambardzumyan, Dolores.

Afiliação

Ross JL; Department of Microbiology and Immunology, Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.
Hambardzumyan D; Departments of Oncological Sciences and Neurosurgery, The Tisch Cancer Institute, Mount Sinai Icahn School of Medicine, New York, NY, USA. Electronic address: dolores.hambardzumyan@mssm.com.

Immunity ; 56(11): 2469-2471, 2023 Nov 14.

Article em En | MEDLINE | ID: mdl-37967529

ABSTRACT

ABSTRACT

Neutrophils have remained understudied in malignant brain tumors. In a recent issue of Cell, Maas et al. analyze brain tumor-patient samples and demonstrate that the brain microenvironment reprograms infiltrating neutrophils to enhance their longevity and increase their immune-suppressive and pro-angiogenic properties.

Assuntos

Neoplasias; Neutrófilos; Humanos; Encéfalo; Neoplasias/patologia; Microambiente Tumoral

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias / Neutrófilos Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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