Identification and characterization of calreticulin as a novel plasminogen receptor.

Bharadwaj, Alamelu G; Okura, Gillian C; Woods, John W; Allen, Erica A; Miller, Victoria A; Kempster, Emma; Hancock, Mark A; Gujar, Shashi; Slibinskas, Rimantas; Waisman, David M

Bharadwaj, Alamelu G; Okura, Gillian C; Woods, John W; Allen, Erica A; Miller, Victoria A; Kempster, Emma; Hancock, Mark A; Gujar, Shashi; Slibinskas, Rimantas; Waisman, David M.

Afiliação

Bharadwaj AG; Departments of Pathology, Dalhousie University, Halifax, Nova Scotia, Canada; Biochemistry and Molecular Biology, Dalhousie University, Halifax, Nova Scotia, Canada.
Okura GC; Departments of Pathology, Dalhousie University, Halifax, Nova Scotia, Canada.
Woods JW; Biochemistry and Molecular Biology, Dalhousie University, Halifax, Nova Scotia, Canada.
Allen EA; Departments of Pathology, Dalhousie University, Halifax, Nova Scotia, Canada.
Miller VA; Departments of Pathology, Dalhousie University, Halifax, Nova Scotia, Canada.
Kempster E; Departments of Pathology, Dalhousie University, Halifax, Nova Scotia, Canada.
Hancock MA; McGill SPR-MS Facility, McGill University, Montréal, Québec, Canada.
Gujar S; Departments of Pathology, Dalhousie University, Halifax, Nova Scotia, Canada.
Slibinskas R; Life Sciences Center, Institute of Biotechnology, Vilnius University, Vilnius, Lithuania.
Waisman DM; Departments of Pathology, Dalhousie University, Halifax, Nova Scotia, Canada; Biochemistry and Molecular Biology, Dalhousie University, Halifax, Nova Scotia, Canada. Electronic address: david.waisman@dal.ca.

J Biol Chem ; 300(1): 105465, 2024 Jan.

Article em En | MEDLINE | ID: mdl-37979915

Assuntos

Calreticulina; Plasminogênio; Animais; Bovinos; Humanos; Calreticulina/genética; Calreticulina/isolamento & purificação; Calreticulina/metabolismo; Fibrinolisina/metabolismo; Plasminogênio/genética; Plasminogênio/metabolismo; Ativador de Plasminogênio Tecidual/metabolismo; Ativador de Plasminogênio Tipo Uroquinase/metabolismo; Domínios Proteicos/genética; Mutação; Proteínas Recombinantes/genética; Proteínas Recombinantes/metabolismo; Técnicas de Inativação de Genes; Linhagem Celular Tumoral; Neoplasias/fisiopatologia

Palavras-chave

calreticulin; plasmin; plasminogen; plasminogen regulation; tissue plasminogen activator

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plasminogênio / Calreticulina Limite: Animals / Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article

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