Effect of Glutamate Antibody F(ab)2 Fragments on Memory Changes in Aged C57BL/6 Mice.
Bull Exp Biol Med
; 175(6): 762-764, 2023 Oct.
Article
em En
| MEDLINE
| ID: mdl-37987943
ABSTRACT
Intranasal administration of F(ab)2 fragments of anti-glutamate antibodies to 12-month-old C57BL/6 mice improves passive avoidance conditioning and have no effect on horizontal and vertical locomotor activity in the open-field test. In contrast to full-length antibodies to glutamate, their F(ab)2 fragments significantly increase the number of animals developed a conditioned passive avoidance reflex.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ácido Glutâmico
/
Anticorpos
Limite:
Animals
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article