A Highly Sensitive and Specific Non-Invasive Test through Genome-Wide 5-Hydroxymethylation Mapping for Early Detection of Lung Cancer.

Ren, Yijiu; Zhang, Zhou; She, Yunlang; He, Yayi; Li, Dongdong; Shi, Yixiang; He, Chuan; Yang, Yang; Zhang, Wei; Chen, Chang

Ren, Yijiu; Zhang, Zhou; She, Yunlang; He, Yayi; Li, Dongdong; Shi, Yixiang; He, Chuan; Yang, Yang; Zhang, Wei; Chen, Chang.

Afiliação

Ren Y; Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, 200433, China.
Zhang Z; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.
She Y; Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, 200433, China.
He Y; Department of Oncology, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Li D; Shanghai Epican Genetech, Co., Ltd., Shanghai, China.
Shi Y; Bionova (Shanghai) Medical Technology Co., Ltd, Shanghai, China.
He C; Department of Chemistry, The University of Chicago, Chicago, IL, 60637, USA.
Yang Y; The Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, 60637, USA.
Zhang W; Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, 200433, China.
Chen C; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.

Small Methods ; 8(3): e2300747, 2024 Mar.

Article em En | MEDLINE | ID: mdl-37990399

Assuntos

Carcinoma Pulmonar de Células não Pequenas; Ácidos Nucleicos Livres; Neoplasias Pulmonares; Carcinoma de Pequenas Células do Pulmão; Humanos; Biomarcadores Tumorais/genética; Carcinoma Pulmonar de Células não Pequenas/diagnóstico; Carcinoma Pulmonar de Células não Pequenas/genética; Ácidos Nucleicos Livres/genética; Detecção Precoce de Câncer/métodos; Neoplasias Pulmonares/diagnóstico por imagem; Neoplasias Pulmonares/genética; Estudos de Casos e Controles

Palavras-chave

5-hydroxymethylcytosine; cell-free DNA; diagnosis; lung cancer; non-small cell lung cancer

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Carcinoma de Pequenas Células do Pulmão / Ácidos Nucleicos Livres / Neoplasias Pulmonares Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article

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