Gene expression profiles separate endometriosis lesion subtypes and indicate a sensitivity of endometrioma to estrogen suppressive treatments through elevated ESR2 expression.

Marla, Sushma; Mortlock, Sally; Heinosalo, Taija; Poutanen, Matti; Montgomery, Grant W; McKinnon, Brett David

Marla, Sushma; Mortlock, Sally; Heinosalo, Taija; Poutanen, Matti; Montgomery, Grant W; McKinnon, Brett David.

Afiliação

Marla S; Institute for Molecular Bioscience, The University of Queensland, Carmody Rd, Brisbane, QLD, 4067, Australia.
Mortlock S; Institute for Molecular Bioscience, The University of Queensland, Carmody Rd, Brisbane, QLD, 4067, Australia.
Heinosalo T; Institute of Biomedicine, Research Centre for Integrative Physiology and Pharmacology, University of Turku, Turku, 20014, Finland.
Poutanen M; Institute of Biomedicine, Research Centre for Integrative Physiology and Pharmacology, University of Turku, Turku, 20014, Finland.
Montgomery GW; Turku Center for Disease Modelling, University of Turku, 20014, Turku, Finland.
McKinnon BD; Institute for Molecular Bioscience, The University of Queensland, Carmody Rd, Brisbane, QLD, 4067, Australia.

BMC Med ; 21(1): 460, 2023 11 23.

Article em En | MEDLINE | ID: mdl-37996888

Assuntos

Endometriose; Doenças Peritoneais; Feminino; Humanos; Endometriose/tratamento farmacológico; Endometriose/genética; Transcriptoma; Endométrio/metabolismo; Endométrio/patologia; Doenças Peritoneais/metabolismo; Doenças Peritoneais/patologia; Estrogênios/metabolismo; Receptor beta de Estrogênio/genética; Receptor beta de Estrogênio/metabolismo

Palavras-chave

Endometriosis; Gene expression; Heterogeneity; Oestrogen receptor; Subtypes; Treatment

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Peritoneais / Endometriose Limite: Female / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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