Deficiency of BMAL1 promotes ROS generation and enhances IgE-dependent degranulation in mast cells.

Nagasaka, Yuka; Nakamura, Yuki; Tran, Nguyen Quoc Vuong; Kobayashi, Yoshiaki; Nakano, Nobuhiro; Nakao, Atsuhito

Nagasaka, Yuka; Nakamura, Yuki; Tran, Nguyen Quoc Vuong; Kobayashi, Yoshiaki; Nakano, Nobuhiro; Nakao, Atsuhito.

Afiliação

Nagasaka Y; Department of Immunology, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan.
Nakamura Y; Department of Immunology, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan.
Tran NQV; Department of Immunology, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan.
Kobayashi Y; Department of Immunology, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan.
Nakano N; Atopy Research Center, Juntendo University School of Medicine, Tokyo, Japan.
Nakao A; Department of Immunology, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan; Atopy Research Center, Juntendo University School of Medicine, Tokyo, Japan; Yamanashi GLIA Center, University of Yamanashi, Yamanashi, Japan. Electronic address: anakao@yamanashi.ac.jp.

Biochem Biophys Res Commun ; 690: 149295, 2024 Jan 01.

Article em En | MEDLINE | ID: mdl-38000295

Assuntos

Fatores de Transcrição ARNTL; Mastócitos; Animais; Camundongos; Fatores de Transcrição ARNTL/genética; Fatores de Transcrição ARNTL/metabolismo; Degranulação Celular; Imunoglobulina E/metabolismo; Mastócitos/metabolismo; Mercaptoetanol/metabolismo; Camundongos Knockout; Espécies Reativas de Oxigênio/metabolismo

Palavras-chave

Bmal1; Degranulation; IgE; Mast cells; ROS

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Transcrição ARNTL / Mastócitos Limite: Animals Idioma: En Ano de publicação: 2024 Tipo de documento: Article

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