Carfilzomib suppressed LDHA-mediated metabolic reprogramming by targeting ATF3 in esophageal squamous cell carcinoma.

Chen, Lu; Shi, Huanying; Zhang, WenXin; Zhu, Yongjun; Chen, Haifei; Wu, Zimei; Qi, Huijie; Liu, Jiafeng; Zhong, Mingkang; Shi, Xiaojin; Wang, Tianxiao; Li, Qunyi

Chen, Lu; Shi, Huanying; Zhang, WenXin; Zhu, Yongjun; Chen, Haifei; Wu, Zimei; Qi, Huijie; Liu, Jiafeng; Zhong, Mingkang; Shi, Xiaojin; Wang, Tianxiao; Li, Qunyi.

Afiliação

Chen L; Department of Pharmacy, Huashan Hospital, Fudan University, Shanghai, China.
Shi H; Department of Pharmacy, Huashan Hospital, Fudan University, Shanghai, China.
Zhang W; Department of Pharmacy, Huashan Hospital, Fudan University, Shanghai, China.
Zhu Y; Department of Cardio-Thoracic Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Chen H; Department of Pharmacy, Huashan Hospital, Fudan University, Shanghai, China.
Wu Z; Department of Pharmacy, Huashan Hospital, Fudan University, Shanghai, China.
Qi H; Department of Pharmacy, Huashan Hospital, Fudan University, Shanghai, China.
Liu J; Department of Pharmacy, Huashan Hospital, Fudan University, Shanghai, China.
Zhong M; Department of Pharmacy, Huashan Hospital, Fudan University, Shanghai, China.
Shi X; Department of Pharmacy, Huashan Hospital, Fudan University, Shanghai, China.
Wang T; Department of Pharmacy, Huashan Hospital, Fudan University, Shanghai, China. Electronic address: wangtianxiao0512@163.com.
Li Q; Department of Pharmacy, Huashan Hospital, Fudan University, Shanghai, China. Electronic address: liqunyi@huashan.org.cn.

Biochem Pharmacol ; 219: 115939, 2024 01.

Article em En | MEDLINE | ID: mdl-38000560

Assuntos

Fator 3 Ativador da Transcrição; Antineoplásicos; Carcinoma de Células Escamosas; Neoplasias Esofágicas; Oligopeptídeos; Neoplasias Esofágicas/tratamento farmacológico; Carcinoma de Células Escamosas/tratamento farmacológico; Oligopeptídeos/farmacologia; Linhagem Celular Tumoral; Antineoplásicos/farmacologia; Xenoenxertos; Transplante de Neoplasias; Humanos; Animais; Camundongos; Camundongos Endogâmicos BALB C; Proliferação de Células/efeitos dos fármacos; Carcinogênese/efeitos dos fármacos; Apoptose; Reprogramação Metabólica/efeitos dos fármacos; Fator 3 Ativador da Transcrição/metabolismo

Palavras-chave

ATF3; Carfilzomib; Esophageal squamous cell carcinoma; LDHA; Metabolic reprogramming

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oligopeptídeos / Neoplasias Esofágicas / Carcinoma de Células Escamosas / Fator 3 Ativador da Transcrição / Antineoplásicos Limite: Animals / Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google