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An automated high inoculation density fed-batch bioreactor, enabled through N-1 perfusion, accommodates clonal diversity and doubles titers.
Olin, Mikayla; Wolnick, Nicolas; Crittenden, Hunter; Quach, Anthony; Russell, Brian; Hendrick, Shannon; Armstrong, Julia; Webster, Thaddaeus; Hadley, Brian; Dickson, Marissa; Hodgkins, Jessica; Busa, Kevin; Connolly, Roger; Downey, Brandon.
Afiliação
  • Olin M; Research and Development, Lonza Biologics, Bend, Oregon, USA.
  • Wolnick N; Research and Development, Lonza Biologics, Bend, Oregon, USA.
  • Crittenden H; Research and Development, Lonza Biologics, Bend, Oregon, USA.
  • Quach A; Research and Development, Lonza Biologics, Bend, Oregon, USA.
  • Russell B; Research and Development, Lonza Biologics, Bend, Oregon, USA.
  • Hendrick S; Research and Development, Lonza Biologics, Bend, Oregon, USA.
  • Armstrong J; Research and Development, Lonza Biologics, Bend, Oregon, USA.
  • Webster T; Research and Development, Lonza Biologics, Portsmouth, New Hampshire, USA.
  • Hadley B; Research and Development, Lonza Biologics, Portsmouth, New Hampshire, USA.
  • Dickson M; Research and Development, Lonza Biologics, Portsmouth, New Hampshire, USA.
  • Hodgkins J; Research and Development, Lonza Biologics, Portsmouth, New Hampshire, USA.
  • Busa K; Research and Development, Lonza Biologics, Portsmouth, New Hampshire, USA.
  • Connolly R; Research and Development, Lonza Biologics, Portsmouth, New Hampshire, USA.
  • Downey B; Research and Development, Lonza Biologics, Bend, Oregon, USA.
Biotechnol Prog ; 40(2): e3410, 2024.
Article em En | MEDLINE | ID: mdl-38013663
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Reatores Biológicos / Anticorpos Monoclonais Limite: Animals Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Reatores Biológicos / Anticorpos Monoclonais Limite: Animals Idioma: En Ano de publicação: 2024 Tipo de documento: Article