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Loss of cis-PTase function in the liver promotes a highly penetrant form of fatty liver disease that rapidly transitions to hepatocellular carcinoma.
Singh, Abhishek K; Chaube, Balkrishna; Citrin, Kathryn M; Fowler, Joseph Wayne; Lee, Sungwoon; Catarino, Jonatas; Knight, James; Lowery, Sarah; Shree, Sonal; Boutagy, Nabil; Ruz-Maldonado, Inmaculada; Harry, Kathy; Shanabrough, Marya; Ross, Trenton Thomas; Malaker, Stacy; Suárez, Yajaira; Fernández-Hernando, Carlos; Grabinska, Kariona; Sessa, William C.
Afiliação
  • Singh AK; Department of Pharmacology, and Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, Connecticut, 06520, USA.
  • Chaube B; Department of Comparative Medicine, Yale Center for Molecular and Systems Metabolism and Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT, USA.
  • Citrin KM; Department of Comparative Medicine, Yale Center for Molecular and Systems Metabolism and Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT, USA.
  • Fowler JW; Department of Pharmacology, and Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, Connecticut, 06520, USA.
  • Lee S; Department of Pharmacology, and Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, Connecticut, 06520, USA.
  • Catarino J; Integrative Cell Signaling and Neurobiology of Metabolism Program, Department of Comparative Medicine, Yale University School of Medicine, New Haven, CT, USA.
  • Knight J; Department of Genetics, Yale School of Medicine, New Haven, CT, USA.
  • Lowery S; Chemistry Research Building, Yale University, New Haven, CT, USA.
  • Shree S; Molecular Biophysics & Biochemistry, Yale University, New Haven, CT, USA.
  • Boutagy N; Department of Pharmacology, and Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, Connecticut, 06520, USA.
  • Ruz-Maldonado I; Department of Comparative Medicine, Yale Center for Molecular and Systems Metabolism and Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT, USA.
  • Harry K; Department of Internal Medicine, Yale University, New Haven, CT, USA.
  • Shanabrough M; Integrative Cell Signaling and Neurobiology of Metabolism Program, Department of Comparative Medicine, Yale University School of Medicine, New Haven, CT, USA.
  • Ross TT; Internal Medicine Research Unit (IMRU), Pfizer, Cambridge, MA, USA.
  • Malaker S; Chemistry Research Building, Yale University, New Haven, CT, USA.
  • Suárez Y; Department of Comparative Medicine, Yale Center for Molecular and Systems Metabolism and Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT, USA.
  • Fernández-Hernando C; Department of Pathology, Yale University School of Medicine, New Haven, CT, USA.
  • Grabinska K; Department of Comparative Medicine, Yale Center for Molecular and Systems Metabolism and Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT, USA.
  • Sessa WC; Department of Pathology, Yale University School of Medicine, New Haven, CT, USA.
bioRxiv ; 2023 Nov 15.
Article em En | MEDLINE | ID: mdl-38014178
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article