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Nonfucosylation of an anti-TIGIT antibody enhances FcγR engagement, driving innate immune activation and antitumor activity.
Smith, Alyson J; Thurman, Robert E; Zeng, Weiping; Grogan, Bryan; Lucas, Sasha; Gutierrez, Guadalupe; Heiser, Ryan A; Wo, Serena W; Blackmarr, Amber; Peterson, Scott; Gardai, Shyra J.
Afiliação
  • Smith AJ; Research Department, Seagen, Bothell, WA, United States.
  • Thurman RE; Research Department, Seagen, Bothell, WA, United States.
  • Zeng W; Research Department, Seagen, Bothell, WA, United States.
  • Grogan B; Research Department, Seagen, Bothell, WA, United States.
  • Lucas S; Research Department, Seagen, Bothell, WA, United States.
  • Gutierrez G; Research Department, Seagen, Bothell, WA, United States.
  • Heiser RA; Research Department, Seagen, Bothell, WA, United States.
  • Wo SW; Research Department, Seagen, Bothell, WA, United States.
  • Blackmarr A; Research Department, Seagen, Bothell, WA, United States.
  • Peterson S; Research Department, Seagen, Bothell, WA, United States.
  • Gardai SJ; Research Department, Seagen, Bothell, WA, United States.
Front Immunol ; 14: 1280986, 2023.
Article em En | MEDLINE | ID: mdl-38022590
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de IgG / Neoplasias Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de IgG / Neoplasias Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article