Redefining metalloproteases specificity through network proteolysis.

Kollet, Orit; Das, Alakesh; Karamanos, Nikos; Auf dem Keller, Ulrich; Sagi, Irit

Kollet, Orit; Das, Alakesh; Karamanos, Nikos; Auf dem Keller, Ulrich; Sagi, Irit.

Afiliação

Kollet O; The Weizmann Institute of Science, Department of Immunology and Regenerative Biology, Rehovot, Israel.
Das A; The Weizmann Institute of Science, Department of Immunology and Regenerative Biology, Rehovot, Israel.
Karamanos N; University of Patras, Biochemistry, Biochemical Analysis and Matrix Pathobiology Research Group, Laboratory of Biochemistry, Department of Chemistry, Patras, Greece.
Auf dem Keller U; Technical University of Denmark, Department of Biotechnology and Biomedicine, Lyngby, Denmark.
Sagi I; The Weizmann Institute of Science, Department of Immunology and Regenerative Biology, Rehovot, Israel. Electronic address: irit.sagi@weizmann.ac.il.

Trends Mol Med ; 30(2): 147-163, 2024 Feb.

Article em En | MEDLINE | ID: mdl-38036391

Assuntos

Metaloproteases; Neoplasias; Humanos; Proteólise; Metaloproteases/análise; Metaloproteases/metabolismo; Neoplasias/metabolismo; Matriz Extracelular/metabolismo; Inflamação/metabolismo; Microambiente Tumoral

Palavras-chave

biomarkers; degradomics; extracellular matrix (ECM) remodeling; matrix metalloproteases (MMPs); protease specificity; proteolytic network

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Metaloproteases / Neoplasias Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article

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