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The suppressive efficacy of THZ1 depends on KRAS mutation subtype and is associated with super-enhancer activity and the PI3K/AKT/mTOR signalling in pancreatic ductal adenocarcinoma: A hypothesis-generating study.
Huang, Lei; Yang, Hui; Chen, Kaidi; Yuan, Jing; Li, Jie; Dai, Guanghai; Gu, Mancang; Shi, Yan.
Afiliação
  • Huang L; Department of Oncology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Yang H; Department of Oncology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Chen K; School of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, China.
  • Yuan J; Department of Pathology, Chinese PLA General Hospital, Beijing, China.
  • Li J; Department of Pathology, Chinese PLA General Hospital, Beijing, China.
  • Dai G; Department of Medical Oncology, Chinese PLA General Hospital, Beijing, China.
  • Gu M; School of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, China.
  • Shi Y; Academy of Chinese Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Clin Transl Med ; 13(12): e1500, 2023 12.
Article em En | MEDLINE | ID: mdl-38037549
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Carcinoma Ductal Pancreático Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Carcinoma Ductal Pancreático Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article