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Genetic risk converges on regulatory networks mediating early type 2 diabetes.
Walker, John T; Saunders, Diane C; Rai, Vivek; Chen, Hung-Hsin; Orchard, Peter; Dai, Chunhua; Pettway, Yasminye D; Hopkirk, Alexander L; Reihsmann, Conrad V; Tao, Yicheng; Fan, Simin; Shrestha, Shristi; Varshney, Arushi; Petty, Lauren E; Wright, Jordan J; Ventresca, Christa; Agarwala, Samir; Aramandla, Radhika; Poffenberger, Greg; Jenkins, Regina; Mei, Shaojun; Hart, Nathaniel J; Phillips, Sharon; Kang, Hakmook; Greiner, Dale L; Shultz, Leonard D; Bottino, Rita; Liu, Jie; Below, Jennifer E; Parker, Stephen C J; Powers, Alvin C; Brissova, Marcela.
Afiliação
  • Walker JT; Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN, USA.
  • Saunders DC; Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Rai V; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
  • Chen HH; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Orchard P; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
  • Dai C; Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Pettway YD; Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN, USA.
  • Hopkirk AL; Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Reihsmann CV; Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Tao Y; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
  • Fan S; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
  • Shrestha S; Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Varshney A; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
  • Petty LE; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Wright JJ; Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Ventresca C; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA.
  • Agarwala S; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
  • Aramandla R; Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Poffenberger G; Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Jenkins R; Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Mei S; Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Hart NJ; Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Phillips S; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Kang H; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Greiner DL; Department of Molecular Medicine, Diabetes Center of Excellence, University of Massachusetts Medical School, Worcester, MA, USA.
  • Shultz LD; The Jackson Laboratory, Bar Harbor, ME, USA.
  • Bottino R; Imagine Pharma, Devon, PA, USA.
  • Liu J; Institute of Cellular Therapeutics, Allegheny-Singer Research Institute, Allegheny Health Network, Pittsburgh, PA, USA.
  • Below JE; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
  • Powers AC; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA. scjp@umich.edu.
  • Brissova M; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA. scjp@umich.edu.
Nature ; 624(7992): 621-629, 2023 Dec.
Article em En | MEDLINE | ID: mdl-38049589
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ilhotas Pancreáticas / Predisposição Genética para Doença / Perfilação da Expressão Gênica / Diabetes Mellitus Tipo 2 / Redes Reguladoras de Genes Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ilhotas Pancreáticas / Predisposição Genética para Doença / Perfilação da Expressão Gênica / Diabetes Mellitus Tipo 2 / Redes Reguladoras de Genes Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article