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ß-l-Arabinofurano-cyclitol Aziridines Are Covalent Broad-Spectrum Inhibitors and Activity-Based Probes for Retaining ß-l-Arabinofuranosidases.
Borlandelli, Valentina; Offen, Wendy; Moroz, Olga; Nin-Hill, Alba; McGregor, Nicholas; Binkhorst, Lars; Ishiwata, Akihiro; Armstrong, Zachary; Artola, Marta; Rovira, Carme; Davies, Gideon J; Overkleeft, Herman S.
Afiliação
  • Borlandelli V; Bio-organic Synthesis, Leiden Institute of Chemistry (LIC), Leiden University, Gorlaeus Laboratories, Einsteinweg 55, 2333 CC Leiden, The Netherlands.
  • Offen W; Department of Chemistry, York Structural Biology Laboratory, University of York, Heslington, York YO10 5DD, United Kingdom.
  • Moroz O; Department of Chemistry, York Structural Biology Laboratory, University of York, Heslington, York YO10 5DD, United Kingdom.
  • Nin-Hill A; Departament de Química Inorgànica i Orgànica (Secció de Química Orgànica), Institut de Química Teòrica i Computacional (IQTCUB), Universitat de Barcelona, Martí i Franquès 1, 08028 Barcelona, Spain.
  • McGregor N; Department of Chemistry, York Structural Biology Laboratory, University of York, Heslington, York YO10 5DD, United Kingdom.
  • Binkhorst L; Bio-organic Synthesis, Leiden Institute of Chemistry (LIC), Leiden University, Gorlaeus Laboratories, Einsteinweg 55, 2333 CC Leiden, The Netherlands.
  • Ishiwata A; RIKEN Cluster for Pioneering Research, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
  • Armstrong Z; Bio-organic Synthesis, Leiden Institute of Chemistry (LIC), Leiden University, Gorlaeus Laboratories, Einsteinweg 55, 2333 CC Leiden, The Netherlands.
  • Artola M; Bio-organic Synthesis, Leiden Institute of Chemistry (LIC), Leiden University, Gorlaeus Laboratories, Einsteinweg 55, 2333 CC Leiden, The Netherlands.
  • Rovira C; Departament de Química Inorgànica i Orgànica (Secció de Química Orgànica), Institut de Química Teòrica i Computacional (IQTCUB), Universitat de Barcelona, Martí i Franquès 1, 08028 Barcelona, Spain.
  • Davies GJ; Department of Chemistry, York Structural Biology Laboratory, University of York, Heslington, York YO10 5DD, United Kingdom.
  • Overkleeft HS; Bio-organic Synthesis, Leiden Institute of Chemistry (LIC), Leiden University, Gorlaeus Laboratories, Einsteinweg 55, 2333 CC Leiden, The Netherlands.
ACS Chem Biol ; 18(12): 2564-2573, 2023 Dec 15.
Article em En | MEDLINE | ID: mdl-38051515
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Aziridinas / Cisteína Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Aziridinas / Cisteína Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article