Myocardial steatosis across the spectrum of human health and disease.
Exp Physiol
; 109(2): 202-213, 2024 Feb.
Article
em En
| MEDLINE
| ID: mdl-38063136
ABSTRACT
Preclinical data strongly suggest that myocardial steatosis leads to adverse cardiac remodelling and left ventricular dysfunction. Using 1 H cardiac magnetic resonance spectroscopy, similar observations have been made across the spectrum of health and disease. The purpose of this brief review is to summarize these recent observations. We provide a brief overview of the determinants of myocardial triglyceride accumulation, summarize the current evidence that myocardial steatosis contributes to cardiac dysfunction, and identify opportunities for further research.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Disfunção Ventricular Esquerda
/
Cardiopatias
Limite:
Humans
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article