The Application of Machine Perfusion as an Enhanced ex vivo Model for Optical Imaging.
Annu Int Conf IEEE Eng Med Biol Soc
; 2023: 1-7, 2023 07.
Article
em En
| MEDLINE
| ID: mdl-38083568
ABSTRACT
Optical imaging techniques such as spectral imaging show promise for the assessment of tissue health during surgery; however, the validation and translation of such techniques into clinical practise is limited by the lack of representative tissue models. In this paper, we demonstrate the application of an organ perfusion machine as an ex vivo tissue model for optical imaging. Three porcine livers are perfused at stepped blood oxygen saturations. Over the duration of each perfusion, spectral data of the tissue are captured via diffuse optical spectroscopy and multispectral imaging. These data are synchronised with blood oxygen saturation measurements recorded by the perfusion machine. Shifts in the optical properties of the tissue are demonstrated over the duration of the each perfusion, as the tissue becomes reperfused and as the oxygen saturation is varied.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Imagem Óptica
/
Fígado
Limite:
Animals
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article