NQO-1 activatable NIR photosensitizer for visualization and selective killing of breast cancer cells.
Bioorg Chem
; 143: 107021, 2024 Feb.
Article
em En
| MEDLINE
| ID: mdl-38104499
ABSTRACT
The diagnosis and treatment of breast cancer is of immense importance in improving patient outcomes. The biological marker NAD(P)Hquinone oxidoreductase 1 was utilized to design BrCyS-Q, a near-infrared activatable photosensitizer for breast cancer. BrCyS-Q was successfully employed to diagnose breast cancer cells using fluorescence and photodynamic inhibition. The findings of this research may offer novel insights for the diagnosis and treatment of clinical breast cancer via photodynamic therapy.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fotoquimioterapia
/
Neoplasias da Mama
Limite:
Female
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Humans
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article