Cardiac computed tomography-based assessment of mitral annular calcification in patients undergoing mitral transcatheter edge-to-edge repair.
J Cardiovasc Comput Tomogr
; 18(1): 26-32, 2024.
Article
em En
| MEDLINE
| ID: mdl-38105119
ABSTRACT
BACKGROUND:
The role of assessment of mitral annular calcification (MAC) using cardiac computed tomography (CCT) in mitral transcatheter edge-to-edge repair (TEER) remains unclear. The aim of this study was to investigate the association of MAC assessed by CCT with procedural and clinical outcomes in patients undergoing TEER.METHODS:
We retrospectively analyzed 275 patients who underwent pre-procedural CCT prior TEER. Mitral calcium volume (MCV) and MAC score were measured by CCT. Functional procedural success was defined as residual mitral regurgitation of ≤2+ with mean transmitral gradient of <5 âmmHg at discharge. All-cause mortality within two years after TEER was collected.RESULTS:
MAC was present in 115 of 275 patients (41.8 %). The median MCV was 198 âmm3 (interquartile range [IQR] 84 to 863 âmm3), and the median MAC score was 3 (IQR 2 to 4). Higher MCV and MAC score were inversely related to the rate of functional procedural success, independently of anatomical features of mitral valve. Patients with moderate/severe MAC, defined as MAC score of ≥4, had a lower rate of functional procedural success than those without MAC (56.1 â% vs. 81.3 â%; p â= â0.002). Moreover, higher MCV and MAC score were associated with a higher risk of all-cause mortality within two years, irrespective of baseline characteristics and functional procedural success.CONCLUSIONS:
The presence and burden of MAC assessed by CCT were associated with procedural and clinical outcomes in patients undergoing TEER. The CCT-based assessment of MAC may improve patient selection for TEER.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Calcinose
/
Próteses Valvulares Cardíacas
/
Implante de Prótese de Valva Cardíaca
/
Doenças das Valvas Cardíacas
/
Insuficiência da Valva Mitral
Limite:
Humans
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article