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Tumor-selective effects of active RAS inhibition in pancreatic ductal adenocarcinoma.
Wasko, Urszula N; Jiang, Jingjing; Curiel-Garcia, Alvaro; Wang, Yingyun; Lee, Bianca; Orlen, Margo; Drizyte-Miller, Kristina; Menard, Marie; Dilly, Julien; Sastra, Stephen A; Palermo, Carmine F; Dalton, Tanner; Hasselluhn, Marie C; Decker-Farrell, Amanda R; Chang, Stephanie; Jiang, Lingyan; Wei, Xing; Yang, Yu C; Helland, Ciara; Courtney, Haley; Gindin, Yevgeniy; Zhao, Ruiping; Kemp, Samantha B; Clendenin, Cynthia; Sor, Rina; Vostrejs, Will; Amparo, Amber A; Hibshman, Priya S; Rees, Matthew G; Ronan, Melissa M; Roth, Jennifer A; Bakir, Basil; Badgley, Michael A; Chabot, John A; Kluger, Michael D; Manji, Gulam A; Quintana, Elsa; Wang, Zhengping; Smith, Jacqueline A M; Holderfield, Matthew; Wildes, David; Aguirre, Andrew J; Der, Channing J; Vonderheide, Robert H; Stanger, Ben Z; Singh, Mallika; Olive, Kenneth P.
Afiliação
  • Wasko UN; Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY.
  • Jiang J; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY.
  • Curiel-Garcia A; Revolution Medicines, Inc., Redwood City, CA.
  • Wang Y; Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY.
  • Lee B; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY.
  • Orlen M; Revolution Medicines, Inc., Redwood City, CA.
  • Drizyte-Miller K; Revolution Medicines, Inc., Redwood City, CA.
  • Menard M; University of Pennsylvania Perelman School of Medicine, Department of Medicine.
  • Dilly J; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Sastra SA; Revolution Medicines, Inc., Redwood City, CA.
  • Palermo CF; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
  • Dalton T; Harvard Medical School, Boston, MA.
  • Hasselluhn MC; Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY.
  • Decker-Farrell AR; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY.
  • Chang S; Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY.
  • Jiang L; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY.
  • Wei X; Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY.
  • Yang YC; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY.
  • Helland C; Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY.
  • Courtney H; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY.
  • Gindin Y; Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY.
  • Zhao R; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY.
  • Kemp SB; Revolution Medicines, Inc., Redwood City, CA.
  • Clendenin C; Revolution Medicines, Inc., Redwood City, CA.
  • Sor R; Revolution Medicines, Inc., Redwood City, CA.
  • Vostrejs W; Revolution Medicines, Inc., Redwood City, CA.
  • Amparo AA; Revolution Medicines, Inc., Redwood City, CA.
  • Hibshman PS; Revolution Medicines, Inc., Redwood City, CA.
  • Rees MG; Revolution Medicines, Inc., Redwood City, CA.
  • Ronan MM; Revolution Medicines, Inc., Redwood City, CA.
  • Roth JA; University of Pennsylvania Perelman School of Medicine, Department of Medicine.
  • Bakir B; University of Pennsylvania Perelman School of Medicine, Abramson Cancer Center.
  • Badgley MA; University of Pennsylvania Perelman School of Medicine, Abramson Cancer Center.
  • Chabot JA; University of Pennsylvania Perelman School of Medicine, Department of Medicine.
  • Kluger MD; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Manji GA; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Quintana E; Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Wang Z; The Broad Institute of Harvard and MIT, Cambridge, MA.
  • Smith JAM; The Broad Institute of Harvard and MIT, Cambridge, MA.
  • Holderfield M; The Broad Institute of Harvard and MIT, Cambridge, MA.
  • Wildes D; Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY.
  • Aguirre AJ; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY.
  • Der CJ; Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY.
  • Vonderheide RH; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY.
  • Stanger BZ; Department of Surgery, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY.
  • Singh M; Department of Surgery, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY.
  • Olive KP; Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY.
bioRxiv ; 2023 Dec 04.
Article em En | MEDLINE | ID: mdl-38105998

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article