Eu MOF-enhanced FeNCD nanozymes for fluorescence and highly sensitive colorimetric detection of tetracycline.
Analyst
; 149(3): 815-823, 2024 Jan 29.
Article
em En
| MEDLINE
| ID: mdl-38117163
ABSTRACT
The constrained enzymatic activity and aggregation challenges encountered by small-sized nanozymes pose obstacles to their practical utility, necessitating a strategy to mitigate aggregation and boost enzymatic catalytic efficiency. In this work, a negatively charged Eu MOF was utilized as the encapsulation matrix, encapsulating the small-sized nanozymes FeNCDs into the Eu MOF to synthesize an FeNCDs@Eu MOF. The dispersibility of the encapsulated FeNCDs was increased, and owing to the negative charge of the FeNCDs@Eu MOF, electrostatic pre-concentration of the positively charged target molecule tetracycline (TC) was facilitated, thereby amplifying the enzymatic catalytic efficiency of the FeNCDs. The response of the FeNCDs to TC increased by nearly 6 times upon encapsulation. The TC detection limit (LOD) of the FeNCDs@Eu MOF-based sensor is as low as 11.63 nM. The incorporation of fluorescence detection expanded the linear range of the sensor, rendering it more suitable for practical sample detection.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Colorimetria
/
Európio
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article