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In vitro activity of delafloxacin against anaerobic bacteria compared with other antimicrobials.
Cobo, Fernando; Franco-Acosta, Ana; Martín-Hita, Lina; Rodríguez-Granger, Javier; Sampedro-Martínez, Antonio; Reguera-Márquez, Juan Antonio; Navarro-Marí, José María.
Afiliação
  • Cobo F; Department of Microbiology and Instituto de Investigación Biosanitaria Ibs.GRANADA, University Hospital Virgen de las Nieves, Granada, Spain. Electronic address: fernando.cobo.sspa@juntadeandalucia.es.
  • Franco-Acosta A; Department of Microbiology and Instituto de Investigación Biosanitaria Ibs.GRANADA, University Hospital Virgen de las Nieves, Granada, Spain.
  • Martín-Hita L; Department of Microbiology and Instituto de Investigación Biosanitaria Ibs.GRANADA, University Hospital Virgen de las Nieves, Granada, Spain.
  • Rodríguez-Granger J; Department of Microbiology and Instituto de Investigación Biosanitaria Ibs.GRANADA, University Hospital Virgen de las Nieves, Granada, Spain.
  • Sampedro-Martínez A; Department of Microbiology and Instituto de Investigación Biosanitaria Ibs.GRANADA, University Hospital Virgen de las Nieves, Granada, Spain.
  • Reguera-Márquez JA; Department of Microbiology and Instituto de Investigación Biosanitaria Ibs.GRANADA, University Hospital Virgen de las Nieves, Granada, Spain.
  • Navarro-Marí JM; Department of Microbiology and Instituto de Investigación Biosanitaria Ibs.GRANADA, University Hospital Virgen de las Nieves, Granada, Spain.
Anaerobe ; 85: 102816, 2024 Feb.
Article em En | MEDLINE | ID: mdl-38145709
ABSTRACT
The aim of this study was to describe the in vitro activity of delafloxacin against 230 anaerobic isolates and compare it with the activity of other antimicrobials used against infections caused by anaerobic microorganisms. Minimal inhibitory concentrations (MICs) were lower for delafloxacin than for all other antibiotics tested with the exception of piperacillin-tazobactam and meropenem against Gram-positive anaerobic cocci. Only two (0.8 %) isolates of Bacteroides spp. showed a MIC ≥4 µg/mL. With some exceptions, the present results show lower MICs for delafloxacin in comparison to the other antibiotics used against anaerobes.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções Bacterianas / Cocos Gram-Positivos / Fluoroquinolonas / Anti-Infecciosos Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções Bacterianas / Cocos Gram-Positivos / Fluoroquinolonas / Anti-Infecciosos Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article