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Predictive Value of Pulmonary Artery Distensibility for Short-Term Adverse Clinical Outcomes in Patients with Acute Pulmonary Embolism.
Yang, Fei; Chen, Rong; Yang, Yue; Yu, Yaxi; Yang, Zhixiang; Zou, Dianjun; Pang, Zhiying; Wang, Dawei.
Afiliação
  • Yang F; Department of Medical Imaging, The First Affiliated Hospital of Hebei North University, Zhangjiakou, Hebei, China.
  • Chen R; College of Basic Medicine, Hebei North University, Zhangjiakou, Hebei, China.
  • Yang Y; College of Basic Medicine, Hebei North University, Zhangjiakou, Hebei, China.
  • Yu Y; College of Basic Medicine, Hebei North University, Zhangjiakou, Hebei, China.
  • Yang Z; College of Basic Medicine, Hebei North University, Zhangjiakou, Hebei, China.
  • Zou D; Department of Medical Imaging, The First Affiliated Hospital of Hebei North University, Zhangjiakou, Hebei, China.
  • Pang Z; Department of Medical Imaging, The First Affiliated Hospital of Hebei North University, Zhangjiakou, Hebei, China.
  • Wang D; Department of Thoracic Surgery, The First Affiliated Hospital of Hebei North University, Zhangjiakou, Hebei, China.
Clin Appl Thromb Hemost ; 30: 10760296231224344, 2024.
Article em En | MEDLINE | ID: mdl-38166421
ABSTRACT
We aimed to explore the relationship between pulmonary artery distensibility obtained from computed tomography pulmonary angiography (CTPA) and short-term adverse clinical outcomes in patients with acute pulmonary embolism (APE). We included patients who underwent retrospective electrocardiogram-gated CTPA and were subsequently diagnosed with APE. Patients were categorized into good and poor outcome groups based on short-term clinical outcomes. Pulmonary artery distensibility (AD), right ventricle/left ventricle (RV/LV) ratio, and pulmonary artery obstruction index (PAOI) were measured, and the receiver operating characteristic curves were constructed. Sixty-four patients with APE (good outcome, 46; poor outcome, 18) were enrolled. AD, RV/LV ratio, and PAOI differed significantly between groups (P < 0.05). Pulmonary artery AD in the good outcome group was greater than that in the poor outcome group (P < 0.001). The poor outcome group exhibited a higher RV/LV ratio and PAOI than the good outcome group (P < 0.05). AD and PAOI were independent predictors of adverse clinical outcomes. Areas under the curve for AD and PAOI were 0.860 (95% confidence interval [CI] 0.750-0.934) and 0.675 (95%CI 0.546-0.786), and the combined curve of the AD and RV/LV ratio was 0.906 (95%CI 0.806-0.965). The calibration curve showed a combined curve superior to the other curves. The decision curve showed high clinical application value of the combined curve. Retrospective electrocardiogram-gated CTPA-derived AD could serve as an indicator for predicting short-term adverse clinical outcomes in APE. Combining AD and PAOI has a high predictive value for short-term adverse clinical outcomes.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Embolia Pulmonar / Hominidae Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Embolia Pulmonar / Hominidae Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article