Association of Serum Beta-Carotene with Metabolic Risk Factors among a Work Cohort in Malaysia.
J Nutr Sci Vitaminol (Tokyo)
; 69(6): 463-470, 2023.
Article
em En
| MEDLINE
| ID: mdl-38171819
ABSTRACT
Metabolic syndrome (MetS) poses increased risks for non-communicable diseases, increasing all-cause mortality, disability, and healthcare costs. Beta-carotene as the major carotenoid is identified to play an important role in the pathophysiology of MetS. The present study aimed to investigate the association between serum beta-carotene levels with metabolic syndrome and metabolic risk factors among a cohort of teachers in Peninsular Malaysia. This cross-sectional study investigated a sub-sample of 645 serum samples which were randomly selected for beta-carotene determination. Socio-demographic, lifestyle and metabolic risk factors were measured following standard protocols. There were equal proportions of males and females, with majority Malays (69%) followed by the Chinese (24%) and Indians (6.5%). The prevalence of MetS was 24.8% with abnormal waist circumference and high blood pressure as the most commonly reported metabolic risk factors. The median serum beta-carotene was 5.15 (5.07) µmol/L. Serum beta-carotene in the lowest quartile (Q1) was found to be significantly associated with MetS (OR 5.81; 95% CI 2.96, 11.38) and metabolic risk factors, namely triglycerides (OR 6.38; 95% CI 3.04, 13.35), fasting blood sugar (OR 3.32; 95% CI 1.48, 7.43), HDL-cholesterol (OR 2.88; 95% CI 1.58, 5.26) and waist circumference (OR 2.94; 95% CI 1.73, 5.01), after adjusted for potential confounders. In summary, participants with lower serum beta-carotene had higher odds for MetS and the above-mentioned metabolic risk factors.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Síndrome Metabólica
Tipo de estudo:
Etiology_studies
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Observational_studies
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Prevalence_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Female
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Humans
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Male
País/Região como assunto:
Asia
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article