Proteomics-based screening of AKR1B1 as a therapeutic target and validation study for sepsis-associated acute kidney injury.

Li, Lei; Ling, Zaiqin; Wang, Xingsheng; Zhang, Xinxin; Li, Yun; Gao, Guangsheng

Li, Lei; Ling, Zaiqin; Wang, Xingsheng; Zhang, Xinxin; Li, Yun; Gao, Guangsheng.

Afiliação

Li L; Intensive Care Unit, Shandong Public Health Clinical Center, Shandong University, Jinan, China.
Ling Z; Department of Tubercular Medicine, Shandong Public Health Clinical Center, Shandong University, Jinan, China.
Wang X; Department of Emergency, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Zhang X; Department of Emergency Medicine, Fuyang People's Hospital of Anhui Medical University, Fuyang, China.
Li Y; Intensive Care Unit, Central Hospital Affliated to Shandong First Medical University, Jinan, China.
Gao G; Neurological Intensive Care Unit, Central Hospital Affliated to Shandong First Medical University, Jinan, China.

PeerJ ; 12: e16709, 2024.

Article em En | MEDLINE | ID: mdl-38188141

Assuntos

Injúria Renal Aguda; Sepse; Animais; Ratos; Injúria Renal Aguda/tratamento farmacológico; Aldeído Redutase; Interleucina-6; NF-kappa B; Proteômica; Sepse/complicações; Fator de Necrose Tumoral alfa

Palavras-chave

AKR1B1; Acute kidney injury; Proteomics; Sepsis; Therapy

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sepse / Injúria Renal Aguda Tipo de estudo: Diagnostic_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limite: Animals Idioma: En Ano de publicação: 2024 Tipo de documento: Article

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