Structurally diverse triterpenoid alkaloids from Buxus rugulosa.
J Asian Nat Prod Res
; 26(1): 18-25, 2024 Jan.
Article
em En
| MEDLINE
| ID: mdl-38189299
ABSTRACT
Four new nortriterpenoid alkaloids, namely buxrugulines E-H (1-4), along with five known ones (5-9), were isolated from the twigs and leaves of Buxus rugulosa. Their structures were identified based on extensive NMR data and MS spectroscopic analyses. Our bioassays revealed that compounds 5, 6 and 8 exhibited potent cytotoxicity in vitro against MCF-7 cell lines, with IC50 values ranging from 6.70 to 11.00 µM, respectively.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Triterpenos
/
Buxus
/
Alcaloides
Limite:
Humans
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article