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Analysis of Anxiety, Depression and Fear of Progression at 12 Months Post-Cytoreductive Surgery in the SOCQER-2 (Surgery in Ovarian Cancer-Quality of Life Evaluation Research) Prospective, International, Multicentre Study.
Lakhiani, Aarti; Cummins, Carole; Kumar, Satyam; Long, Joanna; Arora, Vivek; Balega, Janos; Broadhead, Tim; Duncan, Timothy; Edmondson, Richard; Fotopoulou, Christina; Glasspool, Rosalind; Kolomainen, Desiree; Manchanda, Ranjit; McNally, Orla; Morrison, Jo; Mukhopadhyay, Asima; Naik, Raj; Wood, Nick; Sundar, Sudha.
Afiliação
  • Lakhiani A; Institute of Applied Health Research, University of Birmingham, Birmingham B15 2TT, UK.
  • Cummins C; Pan-Birmingham Gynaecological Cancer Centre, City Hospital, Birmingham B18 7QH, UK.
  • Kumar S; Institute of Applied Health Research, University of Birmingham, Birmingham B15 2TT, UK.
  • Long J; University Hospitals Coventry and Warwickshire NHS Trust, Coventry CV2 2DX, UK.
  • Arora V; Institute of Applied Health Research, University of Birmingham, Birmingham B15 2TT, UK.
  • Balega J; School of Clinical Medicine, University of New South Wales, Sydney, NSW 2052, Australia.
  • Broadhead T; Pan-Birmingham Gynaecological Cancer Centre, City Hospital, Birmingham B18 7QH, UK.
  • Duncan T; Leeds Teaching Hospitals NHS Trust, Leeds LS9 7TF, UK.
  • Edmondson R; Norfolk & Norwich University Hospital, Norwich NR4 7UY, UK.
  • Fotopoulou C; Division of Cancer Services, University of Manchester, Manchester M13 9PL, UK.
  • Glasspool R; Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London SW7 2BX, UK.
  • Kolomainen D; Beatson West of Scotland Cancer Centre, NHS Greater Glasgow and Clyde and School of Cancer Sciences, University of Glasgow, Glasgow G12 8QQ, UK.
  • Manchanda R; Kings College NHS Foundation Trust, London W1W 5DT, UK.
  • McNally O; Wolfson Institute of Population Health, Queen Mary University of London, London EC1M 6BQ, UK.
  • Morrison J; Department of Health Services Research, London School of Hygiene & Tropical Medicine, London WC1E 7HT, UK.
  • Mukhopadhyay A; Peter MacCallum Cancer Centre, Melbourne, VIC 3052, Australia.
  • Naik R; Musgrove Park Hospital, Somerset NHS Foundation Trust, Taunton TA1 5DA, UK.
  • Wood N; Kolkata Gynecological Oncology Trials and Translational Research Group, Kolkata 700156, India.
  • Sundar S; Northern Gynaecological Oncology Centre, Queen Elizabeth Hospital, Gateshead Health NHS Foundation Trust, Gateshead NE9 6SX, UK.
Cancers (Basel) ; 16(1)2023 Dec 22.
Article em En | MEDLINE | ID: mdl-38201503
ABSTRACT
Patients with ovarian cancer (OC) often experience anxiety, depression and fear of progression (FOP); however, it is unclear whether surgical complexity has a role to play. We investigated the prevalence of anxiety, depression and FOP at 12 months post-cytoreductive surgery and investigated associations with surgical complexity, patient (age, ethnicity, performance status, BMI) and tumour (stage, disease load) factors. One hundred and forty-one patients with FIGO Stage III-IV OC, who did not have disease progression at 12 months post-surgery, completed the Hospital Anxiety and Depression Scale and FOP short-form questionnaire. Patients underwent surgery with low (40.4%), intermediate (31.2%) and high (28.4%) surgical complexity scores. At 12 months post-surgery, 99 of 141 (70%) patients with advanced OC undergoing surgery experienced clinically significant anxiety, 21 of 141 (14.9%) patients experienced moderate to severe depression and 37 of 140 (26.4%) experienced dysfunctional FOP. No associations were identified between the three different surgical complexity groups with regards to anxiety, depression or FOP scores. Unsurprisingly, given the natural history of the disease, most patients with OC suffer from anxiety, depression and fear of progression after completion of first-line cancer treatment. Surgical complexity at the time of surgery is not associated with a deleterious impact on anxiety, depression or FOP for patients with OC. Patients with OC experience a profound mental health impact and should be offered mental health support throughout their cancer journey.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article