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Synthesis and evaluation of 2,5-substituted pyrimidines as small-molecule gankyrin binders.
Kanabar, Dipti; Kane, Emma I; Chavan, Tejashri; Laflamme, Taylor M; Suarez, Ethan; Goyal, Mimansa; Gupta, Vivek; Spratt, Donald E; Muth, Aaron.
Afiliação
  • Kanabar D; Department of Pharmaceutical Sciences, College of Pharmacy & Health Sciences, St. John's University, Queens, NY 11439, USA.
  • Kane EI; Gustaf H. Carlson School of Chemistry & Biochemistry, Clark University, Worcester, MA 01610, USA.
  • Chavan T; Department of Pharmaceutical Sciences, College of Pharmacy & Health Sciences, St. John's University, Queens, NY 11439, USA.
  • Laflamme TM; Gustaf H. Carlson School of Chemistry & Biochemistry, Clark University, Worcester, MA 01610, USA.
  • Suarez E; Department of Pharmaceutical Sciences, College of Pharmacy & Health Sciences, St. John's University, Queens, NY 11439, USA.
  • Goyal M; Department of Pharmaceutical Sciences, College of Pharmacy & Health Sciences, St. John's University, Queens, NY 11439, USA.
  • Gupta V; Department of Pharmaceutical Sciences, College of Pharmacy & Health Sciences, St. John's University, Queens, NY 11439, USA.
  • Spratt DE; Gustaf H. Carlson School of Chemistry & Biochemistry, Clark University, Worcester, MA 01610, USA.
  • Muth A; Department of Pharmaceutical Sciences, College of Pharmacy & Health Sciences, St. John's University, Queens, NY 11439, USA.
Future Med Chem ; 16(3): 239-251, 2024 02.
Article em En | MEDLINE | ID: mdl-38205637
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína Supressora de Tumor p53 / Neoplasias Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína Supressora de Tumor p53 / Neoplasias Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article