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Derivation of induced pluripotent stem cell SHEHDNi002-A from a 68-year-old Chinese Han Parkinson's disease patient carrying LRRK2 and DNAJC6 mutations.
Liu, Hui; Zhao, Zongbo; Zhao, Jun; Xu, Luran; Li, Jinshi; Zhang, Bei.
Afiliação
  • Liu H; Department of Neurology and Institute of Neurology, the Affiliated Changshu Hospital of Nantong University, Changshu No.2 People's Hospital, 68 Haiyu Road, Suzhou, Jiangsu, China.
  • Zhao Z; Department of Neurology and Institute of Neurology, the Affiliated Changshu Hospital of Nantong University, Changshu No.2 People's Hospital, 68 Haiyu Road, Suzhou, Jiangsu, China.
  • Zhao J; Department of Neurosurgery, Shanghai University of Medicine & HEALTH Sciences Affiliated Zhoupu Hospital, No.1500 Zhouyuan Road, Pudong New Area, Shanghai, China.
  • Xu L; Department of Neurology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200092, China.
  • Li J; Department of Neurology, Shanghai Pudong New Area Peoples' Hospital, Shanghai 201299, China.
  • Zhang B; Department of Neurology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200092, China. Electronic address: zhangbei0227@163.com.
Stem Cell Res ; 75: 103297, 2024 Mar.
Article em En | MEDLINE | ID: mdl-38219303
ABSTRACT
Parkinson's disease (PD) is a common movement disorder. In this study, we generated an induced pluripotent stem cell (iPSC) line from the dermal fibroblasts of a 68-year-old female patient, carrying LRRK2 and DNAJC6 mutations. This iPSC line will be a useful tool for investigating the pathogenesis and for developing treatment for PD.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Células-Tronco Pluripotentes Induzidas Limite: Aged / Female / Humans País/Região como assunto: Asia Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Células-Tronco Pluripotentes Induzidas Limite: Aged / Female / Humans País/Região como assunto: Asia Idioma: En Ano de publicação: 2024 Tipo de documento: Article