[Scientific legacy of Professor A.A. Kasparov. Inductor of endogenous interferon Poludan in the treatment of ocular herpes and other corneal diseases]. / Nauchnoe nasledie professora A.A. Kasparova. Induktor endogennogo interferona Poludan v lechenii oftal'mogerpesa i drugikh zabolevanii rogovitsy.
Vestn Oftalmol
; 139(6): 183-192, 2023.
Article
em Ru
| MEDLINE
| ID: mdl-38235646
ABSTRACT
This article presents a retrospective analysis of the research findings by professor A.A. Kasparov, who developed and implemented a novel approach to treating ocular herpes. The treatment system is fundamentally different from the conventional chemotherapeutic approach and revolves around non-specific immunotherapy using an endogenous interferon inducer - a biosynthetic complex of polyriboadenylic and polyribouridylic acids, known as Poludan. This approach also incorporates personalized cell therapy based on Poludan, along with herpes vaccine aimed at preventing recurrence. The regenerative and antiviral properties of this approach have proven successful in treating other corneal conditions such as adenovirus infections, early postoperative bullous keratopathy, as well as in stimulation of epithelialization after refractive surgeries (photorefractive keratectomy, phototherapeutic keratectomy).
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Polirribonucleotídeos
/
Ceratite Herpética
/
Ceratectomia Fotorrefrativa
/
Doenças da Córnea
Tipo de estudo:
Etiology_studies
/
Observational_studies
Limite:
Humans
Idioma:
Ru
Ano de publicação:
2023
Tipo de documento:
Article