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Phytosomes: A promising delivery system for anticancer agents by using phytochemicals in cancer therapy.
Pooja, Dave; Rupal, Jani; G S, Chakraborthy; Kaushal J, Jani; Vijay, Upadhye; Kahrizi, Danial; Ahmad Mir, Mushtaq; Siddiqui, Samra; Saeed, Mohd.
Afiliação
  • Pooja D; Parul Institute of Pharmacy & Research, Parul University, Vadodara, 391760 Gujarat, India. pooja.dave19176@paruluniversity.ac.in.
  • Rupal J; Parul Institute of Pharmacy & Research, Parul University, Vadodara, 391760 Gujarat, India. rupal.jani@paruluniversity.ac.in.
  • G S C; Parul Institute of Pharmacy & Research, Parul University, Vadodara, 391760 Gujarat, India. g.chakraborthy19159@paruluniversity.ac.in.
  • Kaushal J J; Formulation Development, Non-Oral Department, Sun Pharmaceutical Industries Limited, Tandlja, Vadodara, Gujarat, India. kaushal2910@gmail.com.
  • Vijay U; Department of Life Sciences, Parul Institute of Applied Sciences and Research and Development Cell, Parul University, Vadodara 391760, Gujarat, India. vijay.upadhye82074@paruluniversity.ac.in.
  • Kahrizi D; Agricultural Biotechnology Department, Faculty of Agriculture, Tarbiat Modares University, Tehran, Iran. dkahrizi@gmail.com.
  • Ahmad Mir M; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid university, Abha, 61421, Saudi Arabia. rjani83@gmail.com.
  • Siddiqui S; Department Health Services Management, College of Public Health and Health Informatics, University of Hail, Hail P.O. Box 2240, Saudi Arabia. rjani83@gmail.com.
  • Saeed M; Department of Biology College of Sciences, University of Hail, Hail, Saudi Arabia. mo.saeed@uoh.edu.sa.
  • Tarun Kumar Upadhyay; Department of Life Sciences, Parul Institute of Applied Sciences and Research and Development Cell, Parul University, Vadodara 391760, Gujarat, India. tarun_bioinfo@yahoo.co.in.
Cell Mol Biol (Noisy-le-grand) ; 69(14): 1-8, 2023 12 20.
Article em En | MEDLINE | ID: mdl-38279505
ABSTRACT
Plant extracts have been shown to be effective in treating a variety of ailments; however their hydrophilic nature and unique chemical structure have caused significant hurdles due to their low bioavailability. Phytosomes technology is used to improve the absorption of phytoconstituents that are difficult to absorb. Among the leading deaths in the society is malignancy. The aforementioned consumes remained a big issue for modern chemotherapy since it has yet to be treated in an efficient manner. The goal of this study is to outline the most recent research on the potential use of phytosome complexes for cancer therapy, as well as the formulation processes and mechanism of transportation through phytosomes.Nanotechnology has paved the way for cancer therapy by altering key features of medications and their carriers. Novel drug delivery systems are used to transfer antitumor drugs to the particular site via different nanostructures. Among several unique drug delivery systems, phytosomes are a creative way to transfer phytoactive compounds to the site of action, and several phytosomes formulations are now being used in clinical settings. Phytoconstituents' anti-cancer activities are increased by phytosomal formulations.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nanoestruturas / Neoplasias / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nanoestruturas / Neoplasias / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article