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The influence of lifestyle and biological factors on semen variability.
Lyons, Hannah E; Gyawali, Prabin; Mathews, Nicola; Castleton, Patience; Mutuku, Shadrack M; McPherson, Nicole O.
Afiliação
  • Lyons HE; Robinson Research Institute, The University of Adelaide, Adelaide, SA, 5005, Australia.
  • Gyawali P; Freemasons Centre for Male Health and Wellbeing, The University of Adelaide, Adelaide, SA, 5005, Australia.
  • Mathews N; Discipline of Reproduction and Development, School of Biomedicine, Adelaide Medical School, The University of Adelaide, Level 5, Adelaide Health and Medical Sciences Building, Adelaide, SA, 5000, Australia.
  • Castleton P; Robinson Research Institute, The University of Adelaide, Adelaide, SA, 5005, Australia.
  • Mutuku SM; Freemasons Centre for Male Health and Wellbeing, The University of Adelaide, Adelaide, SA, 5005, Australia.
  • McPherson NO; Discipline of Reproduction and Development, School of Biomedicine, Adelaide Medical School, The University of Adelaide, Level 5, Adelaide Health and Medical Sciences Building, Adelaide, SA, 5000, Australia.
J Assist Reprod Genet ; 41(4): 1097-1109, 2024 Apr.
Article em En | MEDLINE | ID: mdl-38294621
ABSTRACT

PURPOSE:

Semen parameters are subjected to within-individual variability over time. The driving factors for this variability are likely multi-factorial, with healthier lifestyle associated with better semen quality. The extent in which variations in individual's lifestyle contributes to within-individual semen variability is unknown.

METHODS:

A total of 116 repeat semen samples from 29 men aged 19-37 over 6 months were collected. Basic semen analysis as per 5th WHO manual and extended semen parameters (sperm DNA fragmentation, redox potential and lipid peroxidation, sperm binding to hyaluronan and hyperactive motility) were assessed. An additional 39 lifestyle/biological factors (weight, blood pressure, etc.) were collected at each sample including validated health questionnaires SF36 Health Status, Australian Recommend Food Score, and International Physical Activity Questionnaire.

RESULTS:

Only 10 out of the 39 lifestyle factors varied within men across samples including age (P = 0.0024), systolic blood pressure (P = 0.0080), social functioning (P = 0.0340), energy (P = 0.0069), non-alcoholic caffeinated beverages (P = 0.0010), and nutrition (P < 0.0001). The only semen parameter that varied between collections was sperm morphology (coefficient of variation 23.8 (6.1-72.0), P < 0.05). We only observed weak (r < 0.3) to moderate (r > 0.3- < 0.6) correlations between lifestyle factors, including body mass index, waist circumference, nutrition, exercise, blood pressure and semen parameters including sperm count, progressive motility, and sperm DNA fragmentation (P < 0.05).

CONCLUSION:

In healthy men from the general population, semen quality and associated lifestyle factors do not significantly vary over 6 months, indicating that one semen sample is likely sufficient for determining male fertility in this population.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sêmen / Motilidade dos Espermatozoides / Espermatozoides / Fragmentação do DNA / Análise do Sêmen / Estilo de Vida Limite: Adult / Humans / Male Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sêmen / Motilidade dos Espermatozoides / Espermatozoides / Fragmentação do DNA / Análise do Sêmen / Estilo de Vida Limite: Adult / Humans / Male Idioma: En Ano de publicação: 2024 Tipo de documento: Article