Thrombolysis for ischaemic stroke despite direct oral anticoagulation.

Purrucker, Jan C; Meinel, Thomas R; Wilson, Duncan; Xian, Ying; Wu, Teddy Y; Seiffge, David J

Purrucker, Jan C; Meinel, Thomas R; Wilson, Duncan; Xian, Ying; Wu, Teddy Y; Seiffge, David J.

Afiliação

Purrucker JC; Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany jan.purrucker@med.uni-heidelberg.de.
Meinel TR; Department of Neurology and Stroke Research Center Bern, Inselspital Bern, University of Bern, Bern, Switzerland.
Wilson D; New Zealand Brain Research Institute, Christchurch, New Zealand.
Xian Y; The University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Wu TY; Department of Neurology, Christchurch Hospital, Christchurch, New Zealand.
Seiffge DJ; Department of Neurology and Stroke Research Center Bern, Inselspital Bern, University of Bern, Bern, Switzerland.

Stroke Vasc Neurol ; 2024 Jan 31.

Article em En | MEDLINE | ID: mdl-38296587

ABSTRACT

ABSTRACT

Intravenous thrombolysis is not recommended in anticoagulated patients receiving direct oral anticoagulants (DOACs) and a recent intake within the last 48 hours in US and European guidelines. However, three observational studies now suggest safety of thrombolysis in patients with recent intake of DOACs, and thus support previous experimental data. In this perspective, the current evidence and practical consequences are discussed.

Palavras-chave

Anticoagulants; Stroke; Thrombolysis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Guideline / Observational_studies Idioma: En Ano de publicação: 2024 Tipo de documento: Article

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