Your browser doesn't support javascript.
loading
microbeMASST: a taxonomically informed mass spectrometry search tool for microbial metabolomics data.
Zuffa, Simone; Schmid, Robin; Bauermeister, Anelize; P Gomes, Paulo Wender; Caraballo-Rodriguez, Andres M; El Abiead, Yasin; Aron, Allegra T; Gentry, Emily C; Zemlin, Jasmine; Meehan, Michael J; Avalon, Nicole E; Cichewicz, Robert H; Buzun, Ekaterina; Terrazas, Marvic Carrillo; Hsu, Chia-Yun; Oles, Renee; Ayala, Adriana Vasquez; Zhao, Jiaqi; Chu, Hiutung; Kuijpers, Mirte C M; Jackrel, Sara L; Tugizimana, Fidele; Nephali, Lerato Pertunia; Dubery, Ian A; Madala, Ntakadzeni Edwin; Moreira, Eduarda Antunes; Costa-Lotufo, Leticia Veras; Lopes, Norberto Peporine; Rezende-Teixeira, Paula; Jimenez, Paula C; Rimal, Bipin; Patterson, Andrew D; Traxler, Matthew F; Pessotti, Rita de Cassia; Alvarado-Villalobos, Daniel; Tamayo-Castillo, Giselle; Chaverri, Priscila; Escudero-Leyva, Efrain; Quiros-Guerrero, Luis-Manuel; Bory, Alexandre Jean; Joubert, Juliette; Rutz, Adriano; Wolfender, Jean-Luc; Allard, Pierre-Marie; Sichert, Andreas; Pontrelli, Sammy; Pullman, Benjamin S; Bandeira, Nuno; Gerwick, William H; Gindro, Katia.
Afiliação
  • Zuffa S; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, San Diego, CA, USA.
  • Schmid R; Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, San Diego, CA, USA.
  • Bauermeister A; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, San Diego, CA, USA.
  • P Gomes PW; Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, San Diego, CA, USA.
  • Caraballo-Rodriguez AM; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, San Diego, CA, USA.
  • El Abiead Y; Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, San Diego, CA, USA.
  • Aron AT; Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
  • Gentry EC; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, San Diego, CA, USA.
  • Zemlin J; Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, San Diego, CA, USA.
  • Meehan MJ; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, San Diego, CA, USA.
  • Avalon NE; Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, San Diego, CA, USA.
  • Cichewicz RH; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, San Diego, CA, USA.
  • Buzun E; Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, San Diego, CA, USA.
  • Terrazas MC; Department of Chemistry and Biochemistry, University of Denver, Denver, CO, USA.
  • Hsu CY; Department of Chemistry, Virginia Tech, Blacksburg, VA, USA.
  • Oles R; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, San Diego, CA, USA.
  • Ayala AV; Center for Microbiome Innovation, University of California San Diego, San Diego, CA, USA.
  • Zhao J; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, San Diego, CA, USA.
  • Chu H; Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA.
  • Kuijpers MCM; Department of Chemistry and Biochemistry, College of Arts and Sciences, University of Oklahoma, Norman, OK, USA.
  • Jackrel SL; Department of Pathology, School of Medicine, University of California San Diego, San Diego, CA, USA.
  • Tugizimana F; Department of Pathology, School of Medicine, University of California San Diego, San Diego, CA, USA.
  • Nephali LP; Department of Pathology, School of Medicine, University of California San Diego, San Diego, CA, USA.
  • Dubery IA; Department of Pathology, School of Medicine, University of California San Diego, San Diego, CA, USA.
  • Madala NE; Department of Pathology, School of Medicine, University of California San Diego, San Diego, CA, USA.
  • Moreira EA; Department of Pathology, School of Medicine, University of California San Diego, San Diego, CA, USA.
  • Costa-Lotufo LV; Department of Pathology, School of Medicine, University of California San Diego, San Diego, CA, USA.
  • Lopes NP; Center for Mucosal Immunology, Allergy, and Vaccines (cMAV), Chiba University-University of California San Diego, San Diego, CA, USA.
  • Rezende-Teixeira P; Department of Ecology, Behavior and Evolution, School of Biological Sciences, University of California San Diego, San Diego, CA, USA.
  • Jimenez PC; Department of Ecology, Behavior and Evolution, School of Biological Sciences, University of California San Diego, San Diego, CA, USA.
  • Rimal B; Department of Biochemistry, Faculty of Science, University of Johannesburg, Johannesburg, South Africa.
  • Patterson AD; International Research and Development, Omnia Nutriology, Omnia Group (Pty) Ltd, Johannesburg, South Africa.
  • Traxler MF; Department of Biochemistry, Faculty of Science, University of Johannesburg, Johannesburg, South Africa.
  • Pessotti RC; Department of Biochemistry, Faculty of Science, University of Johannesburg, Johannesburg, South Africa.
  • Alvarado-Villalobos D; Department of Biochemistry and Microbiology, Faculty of Sciences, Agriculture and Engineering, University of Venda, Thohoyandou, South Africa.
  • Tamayo-Castillo G; Department of BioMolecular Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
  • Chaverri P; Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
  • Escudero-Leyva E; Department of BioMolecular Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
  • Quiros-Guerrero LM; Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
  • Bory AJ; Department of Marine Science, Institute of Marine Science, Federal University of São Paulo, Santos, Brazil.
  • Joubert J; Department of Veterinary and Biomedical Sciences, Pennsylvania State University, University Park, PA, USA.
  • Rutz A; Department of Veterinary and Biomedical Sciences, Pennsylvania State University, University Park, PA, USA.
  • Wolfender JL; Plant and Microbial Biology, College of Natural Resources, University of California Berkeley, Berkeley, CA, USA.
  • Allard PM; Plant and Microbial Biology, College of Natural Resources, University of California Berkeley, Berkeley, CA, USA.
  • Sichert A; Metabolomics and Chemical Profiling, Centro de Investigaciones en Productos Naturales (CIPRONA), Universidad de Costa Rica, San José, Costa Rica.
  • Pontrelli S; Metabolomics and Chemical Profiling, Centro de Investigaciones en Productos Naturales (CIPRONA), Universidad de Costa Rica, San José, Costa Rica.
  • Pullman BS; Escuela de Química, Universidad de Costa Rica, San José, Costa Rica.
  • Bandeira N; Microbial Biotechnology, Centro de Investigaciones en Productos Naturales (CIPRONA) and Escuela de Biología, Universidad de Costa Rica, San José, Costa Rica.
  • Gerwick WH; Escuela de Biología, Universidad de Costa Rica, San José, Costa Rica.
  • Gindro K; Department of Natural Sciences, Bowie State University, Bowie, MD, USA.
Nat Microbiol ; 9(2): 336-345, 2024 Feb.
Article em En | MEDLINE | ID: mdl-38316926
ABSTRACT
microbeMASST, a taxonomically informed mass spectrometry (MS) search tool, tackles limited microbial metabolite annotation in untargeted metabolomics experiments. Leveraging a curated database of >60,000 microbial monocultures, users can search known and unknown MS/MS spectra and link them to their respective microbial producers via MS/MS fragmentation patterns. Identification of microbe-derived metabolites and relative producers without a priori knowledge will vastly enhance the understanding of microorganisms' role in ecology and human health.
Assuntos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Espectrometria de Massas em Tandem / Metabolômica Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Espectrometria de Massas em Tandem / Metabolômica Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article