Metalloproteome plasticity - a factor in bacterial pathogen adaptive responses?
Emerg Top Life Sci
; 8(1): 57-60, 2024 Feb 22.
Article
em En
| MEDLINE
| ID: mdl-38323345
ABSTRACT
Through homeostatic processes, bacterial cells maintain intracytoplasmic metal ions at concentrations which enable the 'correct' metal to be inserted into an enzyme, thereby ensuring function. However, fluctuations in intracytoplasmic metal ion concentrations mean that under different conditions certain enzymes may contain different metals at their active site. This perspective describes examples of such cases and suggests that metalloproteome plasticity may contribute to the dynamic adaptation of pathogens to stresses in the host environment.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Bactérias
/
Metais
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article