Food-related exploration across the menstrual cycle.

ABSTRACT

When deciding what to eat we constantly weigh different aspects of the options at hand and make trade-offs between exploiting opportunities with a known outcome (e.g., eating your usual meal) and exploring novel opportunities with a potentially better outcome (e.g., trying a new dish). Environmental factors, such as scarcity, have previously been shown to tip the balance towards either exploration or exploitation. Studies in animals have further linked female steroid hormones (including estradiol and progesterone) to exploratory behavior. Previous work in humans has suggested that food preferences and food intake also change over the menstrual cycle. However, it remains unknown whether exploratory behavior in food choices also changes across the menstrual phases in humans. In a rating phase, 112 adult women (age range 18-45 years) on or off hormonal birth control rated 40 food items on desirability. In the choice phase, participants made binary choices between food items. On some trials, a surprise box replaced one of the two food options, allowing us to examine exploratory choices. Women off hormonal birth control reported their average cycle length and time since the first day of their last menstruation. Analysis of the percentage surprise choices across the menstrual cycle indicated a small, but significant effect, with exploratory choice behavior tending to increase around the middle of/later during the cycle. This provides preliminary novel evidence that hormonal fluctuations are associated with food-related exploratory choice behavior. Importantly, these effects were observed beyond effects of other food-related factors. Future studies should investigate the nature of these effects using more direct hormonal measures.