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Bathing with wipes impregnated with chlorhexidine gluconate to prevent central line-associated bloodstream infection in critically ill patients: A systematic review with meta-analysis.
Peixoto, Erica Almeida Carvalho; Poveda, Vanessa de Brito; Gnatta, Juliana Rizzo; Oliveira, Ramon Antonio.
Afiliação
  • Peixoto EAC; Faculdade Israelita de Ciências da Saúde Albert Einstein, Programa de Mestrado Profissional em Enfermagem, R. Comendador Elias Jafet, São Paulo, SP, Brazil. Electronic address: ericagpeixoto@hotmail.com.
  • Poveda VB; Departamento de Enfermagem-Médico Cirúrgica, Universidade de São Paulo, Escola de Enfermagem, São Paulo, SP, Brazil. Electronic address: vbpoveda@usp.br.
  • Gnatta JR; Departamento de Enfermagem-Médico Cirúrgica, Universidade de São Paulo, Escola de Enfermagem, São Paulo, SP, Brazil. Electronic address: juliana.gnatta@usp.br.
  • Oliveira RA; Departamento de Enfermagem-Médico Cirúrgica, Universidade de São Paulo, Escola de Enfermagem, São Paulo, SP, Brazil. Electronic address: ramon.oliveira@usp.br.
Am J Infect Control ; 52(6): 731-738, 2024 06.
Article em En | MEDLINE | ID: mdl-38342345
ABSTRACT

BACKGROUND:

Recommendations for different types of bathing to prevent central line-associated bloodstream infections (CLABSI) are still divergent. The objective of this study was to verify whether bed bathing with wipes impregnated with 2% chlorhexidine (CHG) compared to conventional bed bathing is more effective in preventing CLABSI.

METHODS:

Systematic review of the literature by consulting the electronic databases PubMed/Medline, Embase, CINAHL, Scopus, and Web of Science from the date of inception until July 1, 2023, with no language or time restrictions.

RESULTS:

A total of 84,462 studies were examined, of which 6 were included in the meta-analysis. Data from 20,188 critical care patients included in primary studies were analyzed. The meta-analysis found that bed bathing with wipes impregnated with 2% CHG reduced the risk of CLABSI by 48% compared to conventional bed bathing (risk ratio 0.52; 95% confidence interval, 0.37-0.73), and this is moderate-quality evidence. The reduction in length of stay in the intensive care unit and length of hospital stay as well as the risk of death were not significantly different between the study groups. Whether bed bathing with 2% CHG-impregnated wipes increases the occurrence of skin reactions is unclear.

CONCLUSIONS:

This meta-analysis provides moderate-quality evidence that daily bathing with 2% CHG-impregnated wipes is safe and helps prevent CLABSI among adult intensive care unit patients.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Banhos / Clorexidina / Estado Terminal / Infecções Relacionadas a Cateter Tipo de estudo: Risk_factors_studies / Systematic_reviews Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Banhos / Clorexidina / Estado Terminal / Infecções Relacionadas a Cateter Tipo de estudo: Risk_factors_studies / Systematic_reviews Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article