[Levels of serum IgE and eosinophilic granulocytes in women with cancer of the uterine cervix]. / Vrijednosti serumskog IgE i eozinofilnih granulocita u zena s rakom grla maternice.

ABSTRACT

In a homogeneous group of patients with diagnosis ca cervicis uteri III B and eosinophilia the concentration of IgE in serum was studied before and during therapy with radiation. In the group of 17 patients in whom concentrations of IgE before radiation were within normal limits (mean = 40.6), after radiation they did not essentially change (mean = 37.1; t less than tgr; P greater than 0.05) and eosinophilia significantly increased at the end of therapy (t = 3.38; P less than 0.05). In the second group of 16 patients higher concentrations of IgE were found before radiation (means = 251.8) and a significant decrease after radiation (mean = 184.6; t = 2.55; P less than 0.05). Eosinophilia had increased here as well (mean = 12.88; t = 8.29; P less than 0.05). Higher concentrations of IgE and eosinophilia are probably partly due to the lack of specific T-suppressor cells for IgE but also partly due to tumour antigens.