Unlocking the mysteries of milk oligosaccharides: Structure, metabolism, and function.
Carbohydr Polym
; 332: 121911, 2024 May 15.
Article
em En
| MEDLINE
| ID: mdl-38431414
ABSTRACT
Milk oligosaccharides (MOs), complex carbohydrates prevalent in human breast milk, play a vital role in infant nutrition. Serving as prebiotics, they inhibit pathogen adherence, modulate the immune system, and support newborn brain development. Notably, MOs demonstrate significant variations in concentration and composition, both across different species and within the same species. These characteristics of MOs lead to several compelling questions (i) What distinct beneficial functions do MOs offer and how do the functions vary along with their structural differences? (ii) In what ways do MOs in human milk differ from those in other mammals, and what factors drive these unique profiles? (iii) What are the emerging applications of MOs, particularly in the context of their incorporation into infant formula? This review delves into the structural characteristics, quantification methods, and species-specific concentration differences of MOs. It highlights the critical role of human MOs in infant growth and their potential applications, providing substantial evidence to enhance infant health and development.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Leite
/
Leite Humano
Limite:
Animals
/
Female
/
Humans
/
Newborn
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article