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Applications of Engineered Skin Tissue for Cosmetic Component and Toxicology Detection.
Wang, Min; Zhang, Linfeng; Hao, Haojie; Yan, Muyang; Zhu, Ziying.
Afiliação
  • Wang M; College of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing, China.
  • Zhang L; College of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing, China.
  • Hao H; The First Medical Center, Chinese People's Liberation Army General Hospital, Beijing, China.
  • Yan M; The First Medical Center, Chinese People's Liberation Army General Hospital, Beijing, China.
  • Zhu Z; The First Medical Center, Chinese People's Liberation Army General Hospital, Beijing, China.
Cell Transplant ; 33: 9636897241235464, 2024.
Article em En | MEDLINE | ID: mdl-38491929
ABSTRACT
The scale of the cosmetic market is increasing every day. There are many safety risks to cosmetics, but they benefit people at the same time. The skin can become red, swollen, itchy, chronically toxic, and senescent due to the misuse of cosmetics, triggering skin injuries, with contact dermatitis being the most common. Therefore, there is an urgent need for a system that can scientifically and rationally detect the composition and perform a toxicological assessment of cosmetic products. Traditional detection methods rely on instrumentation and method selection, which are less sensitive and more complex to perform. Engineered skin tissue has emerged with the advent of tissue engineering technology as an emerging bioengineering technology. The ideal engineered skin tissue is the basis for building good in vitro structures and physiological functions in this field. This review introduces the existing cosmetic testing and toxicological evaluation methods, the current development status, and the types and characteristics of engineered skin tissue. The application of engineered skin tissue in the field of cosmetic composition detection and toxicological evaluation, as well as the different types of tissue engineering scaffold materials and three-dimensional (3D) organoid preparation approaches, is highlighted in this review to provide methods and ideas for constructing the next engineered skin tissue for cosmetic raw material component analysis and toxicological evaluation.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cosméticos / Dermatite de Contato Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cosméticos / Dermatite de Contato Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article