Sensing of mitochondrial DNA by ZBP1 promotes RIPK3-mediated necroptosis and ferroptosis in response to diquat poisoning.

Lai, Kunmei; Wang, Junjie; Lin, Siyi; Chen, Zhimin; Lin, Guo; Ye, Keng; Yuan, Ying; Lin, Yujiao; Zhong, Chuan-Qi; Wu, Jianfeng; Ma, Huabin; Xu, Yanfang

Lai, Kunmei; Wang, Junjie; Lin, Siyi; Chen, Zhimin; Lin, Guo; Ye, Keng; Yuan, Ying; Lin, Yujiao; Zhong, Chuan-Qi; Wu, Jianfeng; Ma, Huabin; Xu, Yanfang.

Afiliação

Lai K; Department of Nephrology, Blood Purification Research Center, the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China.
Wang J; Research Center for Metabolic Chronic Kidney Disease, the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China.
Lin S; Department of Nephrology, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350212, China.
Chen Z; Central Laboratory, the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China.
Lin G; Department of Nephrology, Blood Purification Research Center, the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China.
Ye K; Research Center for Metabolic Chronic Kidney Disease, the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China.
Yuan Y; Department of Nephrology, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350212, China.
Lin Y; Department of Nephrology, Blood Purification Research Center, the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China.
Zhong CQ; Research Center for Metabolic Chronic Kidney Disease, the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China.
Wu J; Department of Nephrology, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350212, China.
Ma H; Department of Nephrology, Blood Purification Research Center, the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China.
Xu Y; Research Center for Metabolic Chronic Kidney Disease, the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China.

Cell Death Differ ; 31(5): 635-650, 2024 May.

Article em En | MEDLINE | ID: mdl-38493248

Assuntos

DNA Mitocondrial; Ferroptose; Necroptose; Proteínas de Ligação a RNA; Proteína Serina-Treonina Quinases de Interação com Receptores; Animais; Humanos; Masculino; Camundongos; DNA Mitocondrial/metabolismo; DNA Mitocondrial/genética; Ferroptose/efeitos dos fármacos; Camundongos Endogâmicos C57BL; Necroptose/efeitos dos fármacos; Proteínas Quinases/metabolismo; Proteínas Quinases/genética; Proteína Serina-Treonina Quinases de Interação com Receptores/metabolismo; Proteína Serina-Treonina Quinases de Interação com Receptores/genética; Proteínas de Ligação a RNA/metabolismo; Proteínas de Ligação a RNA/genética; Diquat/toxicidade

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA Mitocondrial / Proteínas de Ligação a RNA / Proteína Serina-Treonina Quinases de Interação com Receptores / Ferroptose / Necroptose Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2024 Tipo de documento: Article

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