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Immunotherapy and Cancer: The Multi-Omics Perspective.
Donisi, Clelia; Pretta, Andrea; Pusceddu, Valeria; Ziranu, Pina; Lai, Eleonora; Puzzoni, Marco; Mariani, Stefano; Massa, Elena; Madeddu, Clelia; Scartozzi, Mario.
Afiliação
  • Donisi C; Medical Oncology Unit, Department of Medical Sciences and Public Health, "Azienda Ospedaliero Universitaria" of Cagliari, University of Cagliari, 09042 Cagliari, Italy.
  • Pretta A; Medical Oncology Unit, Department of Medical Sciences and Public Health, "Azienda Ospedaliero Universitaria" of Cagliari, University of Cagliari, 09042 Cagliari, Italy.
  • Pusceddu V; Medical Oncology Unit, Department of Medical Sciences and Public Health, "Azienda Ospedaliero Universitaria" of Cagliari, University of Cagliari, 09042 Cagliari, Italy.
  • Ziranu P; Medical Oncology Unit, Department of Medical Sciences and Public Health, "Azienda Ospedaliero Universitaria" of Cagliari, University of Cagliari, 09042 Cagliari, Italy.
  • Lai E; Medical Oncology Unit, Department of Medical Sciences and Public Health, "Azienda Ospedaliero Universitaria" of Cagliari, University of Cagliari, 09042 Cagliari, Italy.
  • Puzzoni M; Medical Oncology Unit, Department of Medical Sciences and Public Health, "Azienda Ospedaliero Universitaria" of Cagliari, University of Cagliari, 09042 Cagliari, Italy.
  • Mariani S; Medical Oncology Unit, Department of Medical Sciences and Public Health, "Azienda Ospedaliero Universitaria" of Cagliari, University of Cagliari, 09042 Cagliari, Italy.
  • Massa E; Medical Oncology Unit, Department of Medical Sciences and Public Health, "Azienda Ospedaliero Universitaria" of Cagliari, University of Cagliari, 09042 Cagliari, Italy.
  • Madeddu C; Medical Oncology Unit, Department of Medical Sciences and Public Health, "Azienda Ospedaliero Universitaria" of Cagliari, University of Cagliari, 09042 Cagliari, Italy.
  • Scartozzi M; Medical Oncology Unit, Department of Medical Sciences and Public Health, "Azienda Ospedaliero Universitaria" of Cagliari, University of Cagliari, 09042 Cagliari, Italy.
Int J Mol Sci ; 25(6)2024 Mar 21.
Article em En | MEDLINE | ID: mdl-38542536
ABSTRACT
Immunotherapies have revolutionized cancer treatment approaches. Because not all patients respond positively to immune therapeutic agents, it represents a challenge for scientists who strive to understand the mechanisms behind such resistance. In-depth exploration of tumor biology, using novel technologies such as omics science, can help decode the role of the tumor immune microenvironment (TIME) in producing a response to the immune blockade strategies. It can also help to identify biomarkers for patient stratification and personalized treatment. This review aims to explore these new models and highlight their possible pivotal role in changing clinical practice.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Multiômica / Neoplasias Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Multiômica / Neoplasias Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article