Corynoline Suppresses Osteoclastogenesis and Attenuates ROS Activities by Regulating NF-&#954;B/MAPKs and Nrf2 Signaling Pathways.

Jin, Chen; Yu, Xian-Bin; Yang, Jiayi; Lin, Zhen; Ma, Run-Xun; Lin, Bing-Hao; Zhang, Hao-Jie; Dai, Zi-Han; Xue, Kaikai; Xie, Cheng-Long; Zheng, Wenhao; Feng, Yongzeng; Xiao, Jian; Yang, Lei

Corynoline Suppresses Osteoclastogenesis and Attenuates ROS Activities by Regulating NF-κB/MAPKs and Nrf2 Signaling Pathways.

Jin, Chen; Yu, Xian-Bin; Yang, Jiayi; Lin, Zhen; Ma, Run-Xun; Lin, Bing-Hao; Zhang, Hao-Jie; Dai, Zi-Han; Xue, Kaikai; Xie, Cheng-Long; Zheng, Wenhao; Feng, Yongzeng; Xiao, Jian; Yang, Lei.

Afiliação

Jin C; Department of Orthopaedic, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Yu XB; Key Laboratory of Orthopaedics of Zhejiang Province, Wenzhou 325000, China.
Yang J; Department of Orthopaedic, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Lin Z; Key Laboratory of Orthopaedics of Zhejiang Province, Wenzhou 325000, China.
Ma RX; Department of Gynaecology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Lin BH; Key Laboratory of Orthopaedics of Zhejiang Province, Wenzhou 325000, China.
Zhang HJ; Department of Plastic and Aesthetic Surgery, Nanfang Hospital of Southern Medical University, Guangzhou 510515, Guangdong, China.
Dai ZH; Department of Orthopaedic, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Xue K; Key Laboratory of Orthopaedics of Zhejiang Province, Wenzhou 325000, China.
Xie CL; Department of Orthopaedic, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Zheng W; Key Laboratory of Orthopaedics of Zhejiang Province, Wenzhou 325000, China.
Feng Y; Department of Orthopaedic, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Xiao J; Key Laboratory of Orthopaedics of Zhejiang Province, Wenzhou 325000, China.
Yang L; Key Laboratory of Orthopaedics of Zhejiang Province, Wenzhou 325000, China.

J Agric Food Chem ; 72(14): 8149-8166, 2024 Apr 10.

Article em En | MEDLINE | ID: mdl-38551844

Assuntos

Alcaloides de Berberina; Reabsorção Óssea; Osteoporose; Feminino; Humanos; Osteogênese; NF-kappa B/genética; NF-kappa B/metabolismo; Espécies Reativas de Oxigênio/metabolismo; Fator 2 Relacionado a NF-E2/genética; Fator 2 Relacionado a NF-E2/metabolismo; Transdução de Sinais; Osteoclastos; Reabsorção Óssea/tratamento farmacológico; Reabsorção Óssea/genética; Reabsorção Óssea/metabolismo; Osteoporose/tratamento farmacológico; Osteoporose/genética; Osteoporose/metabolismo; Ligante RANK/genética; Ligante RANK/metabolismo; Diferenciação Celular

Palavras-chave

NF-κB/MAPKs pathway; Nrf2 pathway; corynoline; osteoclast; reactive oxygen species

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoporose / Alcaloides de Berberina / Reabsorção Óssea Limite: Female / Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article

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