Macrophage-Capturing Self-Assembly Photosensitizer Nanoparticles Induces Immune Microenvironment Re-Programming and Golgi-Responsive Immunogenic Cell Death in Head and Neck Carcinoma.

Zhou, Zhi-Hang; Zhou, Xin-Yu; Zhang, Yi-Yi; Zhao, Tong-Chao; Li, Jiang; Zhong, Lai-Ping; Pang, Yi-Chuan

Zhou, Zhi-Hang; Zhou, Xin-Yu; Zhang, Yi-Yi; Zhao, Tong-Chao; Li, Jiang; Zhong, Lai-Ping; Pang, Yi-Chuan.

Afiliação

Zhou ZH; Department of Stomatology, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Zhou XY; Department of Oral Pathology, Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, P. R. China.
Zhang YY; Department of Oral and Maxillofacial-Head and Neck Oncology, Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China.
Zhao TC; Department of Oral and Maxillofacial-Head and Neck Oncology, Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China.
Li J; Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, National Clinical Research Center of Stomatology, Shanghai, 200011, China.
Zhong LP; Department of Oral Pathology, Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, P. R. China.
Pang YC; Department of Stomatology, Huashan Hospital, Fudan University, Shanghai, 200040, China.

Adv Healthc Mater ; 13(20): e2400012, 2024 Aug.

Article em En | MEDLINE | ID: mdl-38553781

Assuntos

Neoplasias de Cabeça e Pescoço; Morte Celular Imunogênica; Macrófagos; Nanopartículas; Fármacos Fotossensibilizantes; Microambiente Tumoral; Fármacos Fotossensibilizantes/química; Fármacos Fotossensibilizantes/farmacologia; Neoplasias de Cabeça e Pescoço/imunologia; Neoplasias de Cabeça e Pescoço/patologia; Neoplasias de Cabeça e Pescoço/tratamento farmacológico; Animais; Morte Celular Imunogênica/efeitos dos fármacos; Humanos; Nanopartículas/química; Camundongos; Microambiente Tumoral/efeitos dos fármacos; Macrófagos/efeitos dos fármacos; Macrófagos/metabolismo; Macrófagos/imunologia; Linhagem Celular Tumoral; Complexo de Golgi/metabolismo; Espécies Reativas de Oxigênio/metabolismo; Camundongos Nus; Camundongos Endogâmicos BALB C

Palavras-chave

golgi response; immunogenic death; macrophage capturing; oral squamous cell carcinoma; tumor microenvironment

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fármacos Fotossensibilizantes / Nanopartículas / Microambiente Tumoral / Morte Celular Imunogênica / Neoplasias de Cabeça e Pescoço / Macrófagos Limite: Animals / Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article

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