Advancements in the development of fluorescent chemosensors based on CîN bond isomerization/modulation mechanistic approaches.
Anal Methods
; 16(15): 2198-2228, 2024 Apr 18.
Article
em En
| MEDLINE
| ID: mdl-38567418
ABSTRACT
The CîN bond isomerization/modulation as a fluorescence signalling mechanism was explored by studying the photophysical properties of conformationally restricted molecules. From the beginning, the CîN bond isomerization method has attracted the attention of researchers owing to its simplicity, high selectivity, and sensitivity in fluorescence evaluation. Continuous developments in the field of sensing using CîN bond-containing compounds have been achieved via the customization of the isomerization process around the CîN bond in numerous ways, and the results were obtained in the form of specific discrete photophysical changes. CîN isomerization causes significant fluorescence enhancement in response to detected metal cations and other reactive species (Cys, Hys, ClO-, etc.) straightforwardly and effectively. This review sheds light on the process of CîN bond isomerization/modulation as a signalling mechanism depending on fluorescence changes via conformational restriction. In addition, CîN bond isomerization-based fluorescent sensors have yet to be well reviewed, although several fluorescent sensors based on this signalling mechanism have been reported. Therefore, CîN-based fluorescent sensors are summarized in this review.
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01-internacional
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MEDLINE
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article