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Quality control methods for fruit extracts of Kigelia africana using high performance thin layer chromatography.
Bodiwala, Kunjan B; Banker, Nancy; Lalwani, Rahul; Shah, Mamta B; Gajjar, Anuradha K.
Afiliação
  • Bodiwala KB; Department of Pharmaceutical Chemistry and Quality Assurance, L. M. College of Pharmacy, Ahmedabad, India.
  • Banker N; Department of Pharmaceutical Chemistry and Quality Assurance, L. M. College of Pharmacy, Ahmedabad, India.
  • Lalwani R; Department of Pharmaceutical Chemistry and Quality Assurance, L. M. College of Pharmacy, Ahmedabad, India.
  • Shah MB; Gujarat Technological University, Ahmedabad, India.
  • Gajjar AK; Department of Pharmacognosy, L. M. College of Pharmacy, Ahmedabad, India.
Nat Prod Res ; : 1-9, 2024 Apr 10.
Article em En | MEDLINE | ID: mdl-38597203
ABSTRACT
Kigelia africana is a tree native to Africa but also found in eastern and southern parts of India with reported anti-bacterial, anti-inflammatory, and immunomodulatory activities. Verbascoside, caffeic acid and ferulic acid are important markers for the quality control of the plant. Two different HPTLC methods were developed and validated; method - 1 for estimation of verbascoside and caffeic acid while method - 2 for estimation of caffeic acid and ferulic acid. Developed methods were applied to the methanolic fruit extract to determine the quantities of markers. Both methods were found to be linear, specific, precise, accurate, sensitive and robust. Results indicated that both methods can be used for quantitative determination of verbascoside, caffeic acid and ferulic acid in fruit extract. The developed methods may be utilised as a part of the quality control and standardisation for the raw material and extracts of Kigelia africana and can also aid to chromatographic fingerprinting of the plant.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article