Investigating Disparities in Hypopharyngeal/Laryngeal Cancer Survival in Florida With Geospatial Mapping Analysis.
Cancer Control
; 31: 10732748241246958, 2024.
Article
em En
| MEDLINE
| ID: mdl-38623948
ABSTRACT
OBJECTIVE:
Identify predictors of overall survival (OS) after hypopharyngeal/laryngeal cancer in Florida. MATERIAL ANDMETHODS:
We conducted a retrospective cohort study using data from the Florida Cancer Data System (FCDS) on patients diagnosed with hypopharyngeal or laryngeal cancer from 2010-2017. Primary outcome was OS. Hazard ratios (HRs) were estimated from univariable and multivariable Cox regression models for OS. Data was analyzed from November 1, 2022, to June 30, 2023.RESULTS:
We analyzed 6771 patients, who were primarily male (81.2%), White non-Hispanic (WNH) (78.2%), publicly insured (70.1%), married (51.8%), and residents of urban counties (73.6%). Black patients were more likely to be younger at diagnosis (38.9%), single (43.4%), to have distant SEER stage disease (25.6%). Median OS were lowest among patients who were uninsured (34 months), with hypopharyngeal site disease (18 months), and a smoking history (current 34 months, former 46 months, no smoking 63 months). Multivariable Cox regression analysis showed worse OS for single/unmarried vs married (HR 1.47 [95%CI 1.36-1.59], P < .001), history of tobacco use (current HR 1.62 [95%CI 1.440-1.817], P < .001; former smokers (HR 1.28 [95%CI 1.139-1.437], P < .001) vs no history). Improved OS was observed among White Hispanics (WH) vs WNH (HR .73 [95%CI .655-.817], P < .001) and women vs men (HR .88 [95%CI .807-.954], P = .002). Geographical mapping showed that mortality rates were highest in census tracts with low income and education.CONCLUSION:
Our findings suggest that sociodemographic and clinical factors impact OS from hypopharyngeal/laryngeal cancer in Florida and vary geographically within the state. These results will help guide future public health interventions.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Laríngeas
Limite:
Female
/
Humans
/
Male
País/Região como assunto:
America do norte
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article