Oxidative Transformation of 2-Furylanilines into Indolin-3-ones.
J Org Chem
; 89(9): 6602-6606, 2024 May 03.
Article
em En
| MEDLINE
| ID: mdl-38635314
ABSTRACT
Oxidation of 2-furylaninlies with m-CPBA followed by treatment with a base provides access to functionalized indolin-3-ones. The designed oxidative transformation utilizes an underassessed chemical behavior of furyl-containing amines to form a C-N bond via engaging a ß-carbon atom of the furan core upon a ring-forming step, thereby providing an alternative disconnection toward nitrogen-containing heterocycles.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article