Complement(ing) long-COVID thromboinflammation and pathogenesis.

Lee, John D; Woodruff, Trent M

Lee, John D; Woodruff, Trent M.

Afiliação

Lee JD; School of Biomedical Sciences, University of Queensland, St Lucia, Brisbane, QLD, 4072, Australia.
Woodruff TM; School of Biomedical Sciences, University of Queensland, St Lucia, Brisbane, QLD, 4072, Australia; Queensland Brain Institute, the University of Queensland, St Lucia, Brisbane, QLD, 4072, Australia. Electronic address: t.woodruff@uq.edu.au.

Trends Immunol ; 45(6): 397-399, 2024 Jun.

Article em En | MEDLINE | ID: mdl-38637200

ABSTRACT

ABSTRACT

The persistence or recurrence of symptoms after acute SARS-CoV-2 infection, termed 'long COVID', presents a formidable challenge to global healthcare systems. Recent research by Cervia-Hasler and colleagues delves into the intricate immunological landscape in patients with long COVID, demonstrating an interplay between complement and coagulation, driven by antiviral antibodies and tissue damage.

Assuntos

COVID-19; Proteínas do Sistema Complemento; SARS-CoV-2; Humanos; COVID-19/imunologia; SARS-CoV-2/imunologia; Proteínas do Sistema Complemento/imunologia; Proteínas do Sistema Complemento/metabolismo; Tromboinflamação/imunologia; Coagulação Sanguínea/imunologia; Síndrome de COVID-19 Pós-Aguda; Ativação do Complemento/imunologia; Anticorpos Antivirais/imunologia

Palavras-chave

SARS-CoV-2; coagulation; complement; inflammation; long COVID

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas do Sistema Complemento / SARS-CoV-2 / COVID-19 Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article

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