Your browser doesn't support javascript.
loading
Granulosa cell tumor of the ovary: a series of 6 cases.
da Costa, Rafael Everton Assunção Ribeiro; Silva, Maria Clara Amorim; Cavalcante, Erlan Clayton Xavier; Branco, Rodrigo de Oliveira Castelo; Dos Reis, Cristiane Amaral; Vieira, Sabas Carlos.
Afiliação
  • da Costa REAR; Health Science Center, State University of Piauí, Teresina (PI), Brazil.
  • Silva MCA; Health Science Center, State University of Piauí, Teresina (PI), Brazil.
  • Cavalcante ECX; Health Science Center, State University of Piauí, Teresina (PI), Brazil.
  • Branco ROC; Health Science Center, State University of Piauí, Teresina (PI), Brazil.
  • Dos Reis CA; Clinical Oncology, Oncocenter, Teresina (PI), Brazil.
  • Vieira SC; Tocogynecology, Oncocenter, Teresina (PI), Brazil.
Pan Afr Med J ; 47: 58, 2024.
Article em En | MEDLINE | ID: mdl-38646138
ABSTRACT
Granulosa cell tumor (GCT) is a rare ovarian malignancy that represents only 2-3% of all cases. There are two subtypes of GCT juvenile/JGCT (5% of cases) and adult/AGCT (95% of cases). This study aimed to describe a series of 6 GCT cases. The 6 study patients were managed from June 2011 to November 2022 in a private oncology clinic located in Teresina (PI), Brazil. At diagnosis, the mean patient age was 47 years, and symptoms in 5 patients (83%) were pelvic pain and/or increased abdominal volume. The majority of the patients (N=4/67%) had no comorbidities or findings related to GCT on physical examination. The mean tumor size was 11 cm. Five (83%) tumors were stage Ia and one tumor (17%) was stage III. Regarding tumor subtype, 5 (83%) were AGCT and 1 (17%) was JGCT. Surgical treatment consisted of unilateral salpingo-ophorectomy in 2 patients (33%), total hysterectomy and bilateral salpingo-ophorectomy in 3 patients (50%), and cytoreduction (suboptimal) in 1 patient (17%). After a mean follow-up period of 62.7 months, 5 patients (83%) are still alive and free of disease. One (17%) died from disease progression after 126 months. In the current study, disease-free overall survival was 83%, in a mean follow-up period of 62.7 months.
Assuntos
Palavras-chave

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Tumor de Células da Granulosa / Estadiamento de Neoplasias Limite: Adult / Aged / Female / Humans / Middle aged País/Região como assunto: America do sul / Brasil Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Tumor de Células da Granulosa / Estadiamento de Neoplasias Limite: Adult / Aged / Female / Humans / Middle aged País/Região como assunto: America do sul / Brasil Idioma: En Ano de publicação: 2024 Tipo de documento: Article